ESBD_437605_1753108799535_RFP 25-37 Pricing Attachment 4.xlsx

XLSX spreadsheet 14 KB Posted

Attached to
RFP 25-37 Biotech Downstream Equipment
Solicitation number
RFP_25_37_Biotech_Downstream_Equipment
Issued by
Texas

About this file

This document is a Request for Proposal (RFP) 25-37 Pricing Attachment for a small-scale Tangential Flow Filtration (TFF) system, issued by San Jacinto, seeking to procure one (1) refurbished or new TFF system manufactured no earlier than 2017. The system requirements include a complete setup with computer, preloaded software, a one-year initial warranty, training, delivery, and installation/calibration. Preferred vendor models include Cytiva AKTA Flux, Sartorius SartoFlow Smart, Formulatrix uPULSE, or equivalent alternatives, with specific technical specifications detailing operational parameters such as batch size (0.1L), working volume (minimum 10mL), membrane area (0.01 m2), and process temperature range (2-40°C).

The procurement emphasizes comprehensive technical requirements, including safety features, pressure and flow transmitters, automated control capabilities, and a robust training package that covers system familiarization, applications, health and safety protocols, method setup, and data analysis. The vendor must provide a minimum 24-month manufacturer's warranty, technical support, future software upgrades, onsite call-out timeframes, parts availability, and a lifetime management plan. Shipping is included with lift-gate delivery to the FOB destination, and the vendor must outline warranty exclusions and support details. No specific pricing is listed in the attachment, with the total to be included in a separate line items tab.

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Small Scale TFF

Pricing Attachment 4
Small-scale TFF
Vendor Name:
For No Bid on this Equipment, List No Bid Here:

Quantity of one (1) refurbished or new Cytiva AKTA Flux System, or compatible commodity alternate, built no earlier than 2017. Bids shall include one (1) small-scale TFF system, (complete with computer and preloaded software), initial one (1) year warranty, training, delivery fee, and installation/calibration. Colleges Preferred Models: Cytiva AKTA Flux, Sartorius SartoFlow Smart, Formulatrix uPULSE, or equivalent *Confirmed inclusion of each line within proposal. If there is an additional cost per line, indicate additional price in the Price column.

Specification/Feature*Confirm each line is included in proposalPrice*
Tangential flow filtration (TFF) system designed for concentration and diafiltration of suspended microparticulates, including cell suspensions.
The unit shall include all components necessary for operation. As a minimum these will include feed vessel, pump, filter module, piping, instrumentation, and controls.
The unit shall have a compact flow path to enable high concentration factors to be achieved.
The unit shall be capable of handling a batch size of 0.1L in a single operation.
Minimum working volume of 10mL with 0.01 m2 membrane area.
The unit shall also be capable of handling larger volumes, eg. during diafiltration, by drawing fluid into the feed vessel.
Max process pressure: 3 barg (limited by filter)
Wetted elastomers shall be tested to USP Class VI
The material of construction of the Feed Vessel shall be compatible with requirements for sanitary processing and cleaning
The filter module shall be configurable to contain one membrane cassette or several membrane cassettes in parallel to give a range of membrane areas. The expected range is of the order of 0.01 m2 – 0.4 m2. The filters must be cassette filters or hollow fibre filters or both if possible.
Pressure transmitters shall indicate the retentate pressure upstream and downstream of the filter module and indicate the permeate pressure.
A flow transmitter shall indicate the retentate flow, feed flow and permeate flow.
The recirculation pump shall have local speed control and indication.
Process data collected by transmitters shall be available for export to a PC or laptop (by others) for recording.
Automated control of crossflow rate and/or transmembrane pressure is required.
Permeate flowrate measurement is required on the unit.
The unit shall include relief devices or interlocks as required to provide product and operator safety. The Supplier shall provide details of the safety features with their proposal.
Process temperature 2 - 40°C for Operation up to 50°C for CIP (excluding cassettes)
If the unit is single use, include 1-3 single use kits.
The vendor must provide details of training included with the proposed solution. This training package should include familiarization training and applications training with the system on site at San Jacinto post installation. This training should also include briefing of all associated health and safety requirements associated with instrument operation, maintenance, and troubleshooting. In addition, this training must include method set up and data analysis on the system software
The proposed system should come with a minimum of a 24-month manufacturer’s warranty which should include any associated call out costs, parts and labour for issues encountered during the warranty period. List of exclusions to the warranty must be outlined.
Vendor to provide details on technical support and after sales support.
The vendor should include any future software upgrades required.
The vendor should provide details of onsite call out time frame and online assistance timeframe for both hardware and software issues.
Availability and lead time of any potential parts needed for maintenance should clearly be indicated.
The vendor must provide details of the year of introduction of the proposed solution and a lifetime management plan, i.e., if the proposed solution is to be superseded and if so for how long the proposed solution will be supported and for how long parts will be available.
Shipping included with lift-gate to FOB destination
Include this total in the Line Items Tab - Line Item 1 in IonWave:$ - 0

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