ESBD_437605_1753108798017_RFP 25-37 Pricing Attachment 3.xlsx

XLSX spreadsheet 14 KB Posted

Attached to
RFP 25-37 Biotech Downstream Equipment
Solicitation number
RFP_25_37_Biotech_Downstream_Equipment
Issued by
Texas

About this file

This document is a Request for Proposal (RFP) 25-37 Pricing Attachment for a Pilot-Scale Chromatography System issued by San Jacinto College. The solicitation seeks one (1) refurbished or new Cytiva AKTA Ready Gradient Pilot-scale Chromatography System, or a compatible alternate manufactured no earlier than 2017. The equipment must be capable of handling a 60L batch size in a single operation, with flow rates between 5-55 l/hr, and include a comprehensive package involving the chromatography system, computer with preloaded software, initial one-year warranty, training, delivery, and installation/calibration.

The pricing attachment outlines detailed technical specifications for the chromatography system, including requirements for sanitary design, metallic wetted parts (SS 316L), compatibility with 100 mm diameter columns, and specific instrumentation features such as UV measurement, conductivity and pH measurements, and safety interlocks. The vendor must provide a 24-month manufacturer's warranty covering call-out costs, parts, and labor, along with comprehensive on-site training that includes familiarization, applications training, health and safety briefings, method setup, and data analysis. The system is expected to be powered by 100-120V at 50/60 Hz, with preferred models including Cytiva AKTA Ready, Repligen ARTeSYN, and Sigma-Aldrich Mobius Chrom 2.

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Pilot Scale Chromatography

Pricing Attachment 3
Pilot-Scale Chromatography
Vendor Name:
For No Bid on this Equipment, List No Bid Here:

Quantity of one (1) refurbished or new Cytiva AKTA Ready Gradient Pilot-scale Chromatography System, or compatible commodity alternate, built no earlier than 2017. Bids shall include one (1) pilot-scale chromatography system, (complete with computer and preloaded software), initial one (1) year warranty, training, delivery fee, and installation/calibration. Colleges Preferred Models: Cytiva AKTA Ready, Repligen ARTeSYN, SigmaAldrich Mobius Chrom 2, or equivalent *Confirmed inclusion of each line within proposal. If there is an additional cost per line, indicate additional price in the Price column.

Specification/Feature*Confirm each line is included in proposalPrice*
Chromatography system designed for use in conjunction with pilot scale, 100 mm diameter columns.
The unit shall be a sanitary design, self-venting and fully drainable.
The unit shall include all components necessary for operation. As a minimum these will include inlet valves, pump, piping, air trap, filter housing, column connections, outlet valves, instrumentation, and controls.
The unit shall have a compact flow path and be free standing, mounted on castors.
The unit shall be capable of handling a batch size of 60L in a single operation.
The unit shall have a minimum of 4 inlet valves and 2 outlet valves compatible with tri clamp connections.
The unit shall be capable of delivering flow rates between 5 l/hr. – 55 l/hr.
If not Single use, Metallic wetted parts shall be SS 316L (or equivalent), polished to 0.8-micron Ra or better.
The material of construction shall be compatible with requirements for sanitary processing and cleaning, ideally stainless steel.
The unit shall be compatible with a 100 mm chromatography column joined by tri clamp connections
The unit shall be capable of delivering flow thorough the column in upflow and downflow directions.
The following gives the minimum requirement for instrumentation and control. The Supplier may provide additional functionality if this is standard on their unit.
The system shall have a flow indicator and flow transmitter.
Pressure transmitters shall indicate the pre-column pressure. A pressure switch or pressure alarm shall be available in case of pressure increase.
The pump shall have local speed control and indication.
Automated diaphragm valves shall be provided controlling system inlet, fluid pathway and outlets.
Process data collected by transmitters shall be available for export to a PC or laptop for recording.
UV measurement at 254 nm and 280 nm shall be available at the column outlet.
Conductivity and pH measurements shall be available at the column outlet.
The unit shall include relief devices or interlocks as required to provide product and operator safety. The Supplier shall provide details of the safety features with their proposal.
Pressure alarms and pump shutoffs shall be available and the alarm limits adjustable by the user
An emergency stop button shall be present on the system
The unit will be powered by the following electric source if available: 100-120V at 50/60 Hz. If not please specify
Equipment arrangement is to allow for ease of maintenance and accessibility.
All unit surfaces must allow for ease of cleaning and decontamination.
The vendor must provide details of training included with the proposed solution. This training package should include familiarisation training and applications training with the system on site at San Jacinto College post installation. This training should also include briefing of all associated health and safety requirements associated with instrument operation, maintenance, and troubleshooting. In addition, this training must include method set up and data analysis on the system software
The proposed system should come with a minimum of a 24-month manufacturer’s warranty which should include any associated call out costs, parts and labour for issues encountered during the warranty period. List of exclusions to the warranty must be outlined.
Vendor to provide details on technical support and after sales support.
The vendor should provide details of onsite call out time frame and online assistance timeframe for both hardware and software issues.
Availability and lead time of any potential parts needed for maintenance should clearly be indicated.
Shipping included with lift-gate to FOB destination
Include this total in the Line Items Tab - Line Item 1 in IonWave:$ - 0

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