Amendment 5 CC4CARB.pdf

This amendment modifies a request for proposals for the creation of a Chemistry Center for Combating Antibiotic-Resistant Bacteria. The amendment extends the proposal due date from March 23, 2020 to March 25, 2020 at 3:00PM EST in response to the COVID-19 pandemic. Offerors must acknowledge receipt of Amendment 5, which was issued by Jonathan Bryan as the contracting officer from the National Institute of Allergy and Infectious Diseases.

The purpose of the solicitation is to establish an innovative chemistry center to design, synthesize, and deliver rationally designed compound libraries to support antibacterial drug discovery programs targeting Gram-negative bacteria. The center will address priorities in the National Action Plan for Combating Antibiotic-Resistant Bacteria. It requires capabilities in chemical library design, compound synthesis, and compound management for storage and distribution to researchers. A single principal investigator accountable for coordination and project management is sought, with skills in synthetic chemistry.