Data coordinating and operations center for the echo idea states pediatric clinical trials network

Active Cooperative Agreement Awarded Last action

Award ID
U24OD038400
Recipient
Awarding agency
Obligated
$29,823,599

Award facts

Assistance listing
93.310 Trans-NIH Research Support
Completion date 27% complete
Funding agency
Office of the Director National Institutes of Health, Department of Health and Human Services
Place of performance
Kansas City, KS 66160, USA

Award details come from USAspending.gov.

Description

Abstract
Many children, particularly those in rural and underserved communities, lack vital access to pediatric clinical trials. This project addresses this disparity by proposing a data coordinating and operations center (dcoc) for the NIH environmental influences on child health outcomes (echo) idea states pediatric clinical trials network (ispctn), a national leader in this field. The project acknowledges current challenges faced by these communities, including geographical limitations, lack of trusted local information, logistical hurdles, and healthcare providers unfamiliar with conducting clinical trials. The proposed ispctn dcoc at the university of kansas medical center (kumc) in partnership with the university of nebraska medical center (unmc) aims to bridge this GAP by leveraging the complementary expertise of both institutions. The kumc-unmc dcoc will actively support clinical trial activity by facilitating development, conduct, and results dissemination of multicenter trials focused on rural and underserved children. Additionally, the dcoc will empower researchers, clinicians, and community stakeholders in idea states by providing them with the necessary training and support to build their pediatric clinical research capacity. Finally, the project emphasizes the importance of community engagement. The dcoc will foster collaboration with communities, along with nonprofit and professional societies, to ensure that clinical trials are culturally relevant, rigorously designed, and have a significant impact on child health outcomes. The kumc-unmc dcoc will build upon the outstanding foundation of policy and procedures developed in the first two cycles of the network to further increase academic productivity and enhance the identification, development, execution, and results dissemination of high quality pediatric clinical trials in these areas. The dcoc will integrate quality by design; continuous quality improvement; real-time goals, objectives, indicators, and targets monitoring; multi-faceted professional development; community research engagement and literacy; and learning collaborative approaches to ispctn clinical trial operations and capacity-building. This initiative promises to increase access to clinical trials for a wider range of children, while strengthening pediatric research capabilities in underserved areas. Ultimately, the goal is to deliver high-quality, culturally sensitive clinical trials that generate valuable knowledge and lead to improved health outcomes for children across the united states and beyond.

Transactions

Action Obligated Date
Amendment $241,000
Amendment $0
Amendment $0
Amendment $7,759,000
Amendment $7,759,000
Amendment $0
Amendment $0
Amendment $0
Original award $6,305,599

Subawards

Subrecipient Amount Awarded
Emory University The protocol chair will provide scientific leadership for the development of a network clinical trial conducted in the ECHO ISPCTN. Responsibilities include:… $46,508
The Nemours Foundation Dr. Thao-Ly Phan will serve as Protocol Co-Chair for the PhITT Study and provide scientific, clinical, and operational leadership for study implementation in… $40,028
Board Of Regents Of The University Of Nebraska Clinical Research Monitoring The University of Nebraska Medical Center (UNMC) shall provide clinical research monitoring services for all active study sites… $240,780
Avera Health The PI will serve as the Community Health and Implementation Science Lead and will direct the community-engaged implementation approach for the NOURISH… $6,058
Rhode Island Hospital 1. Collaboration & Conduct • Partner with the Data Coordinating Center (DCOC) to screen, enroll, randomize and follow participants per the protocol. • Provide… $322,494
The Nemours Foundation The PI will provide scientific, clinical, and operational leadership for the NOURISH study and will oversee coordination of activities across participating… $14,010
Dartmouth-Hitchcock Clinic 1. Collaboration & Conduct • Partner with the Data Coordinating Center (DCOC) to screen, enroll, randomize and follow participants per the protocol. • Provide… $322,494
University Of New Mexico $322,494
Pennington Biomedical Research Center Site Responsibilities: 1. Collaboration & Conduct • Partner with the Data Coordinating Center (DCOC) to screen, enroll, randomize and follow participants per… $322,494
Childrens Mercy Hospital $322,494
Prisma Health $322,494
The Nemours Foundation Site Responsibilities: 1. Collaboration & Conduct • Partner with the Data Coordinating Center (DCOC) to screen, enroll, randomize and follow participants per… $322,494
University Of Oklahoma The site responsibilities are as follows: 1. Collaboration & Conduct • Partner with the Data Coordinating Center (DCOC) to screen, enroll, randomize and… $322,494
University Of Louisville Site Responsibilities: 1. Collaboration & Conduct • Partner with the Data Coordinating Center (DCOC) to screen, enroll, randomize and follow participants per… $322,494
Duke University DCRI will provide general development and content support for the ISPCTN part of the ECHOchildren.org website through two tracks. Track 1 will include preparing… $30,336
Board Of Regents Of The University Of Nebraska The UNMC sub-award site, as part of the DCOC and in partnership with the University of Kansas Medical Center, will play a critical role in supporting the… $1,634,460
Show all 16

Quick answers

Who received award U24OD038400?

U24OD038400 was awarded to University Of Kansas Medical Center Research Institute, Inc. by Aggregate Financial Assistance Data (National Institutes of Health) on June 11, 2025.

How much is award U24OD038400 worth?

$29,823,599 has been obligated on U24OD038400.

Which agency awarded U24OD038400?

Aggregate Financial Assistance Data (National Institutes of Health) awarded U24OD038400, with funding from Office of the Director (National Institutes of Health).

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