Prisma Health

Prisma Health, a South Carolina-based tax-exempt nonprofit health system headquartered in Greenville, operates exclusively as a sub-recipient on federal research grants rather than as a prime contractor or grant recipient. The organization has no federal contract prime awardees and no federal grant prime awards; all three recent federal awards in the source are sub-awards under research grants managed by academic institutions.

Prisma Health's federal footprint centers on clinical research support and translational biomedical science. As a sub-recipient, the organization provides clinical expertise, site management, participant enrollment and follow-up, and investigational product dispensing for multi-institutional research protocols. Recent named sub-awards include a March 2026 sub-grant from the University of Kansas Medical Center Research Institute, where Prisma Health serves as a research site responsible for participant screening, enrollment, randomization, study-drug management, timely electronic data capture entry, and monitoring compliance; a January 2026 sub-award under Clemson University's NIH Phase II COBRE application (NIH COBRE P20GM121342) in musculoskeletal health research, where Prisma Health clinical staff mentor early-stage investigators and provide scientific guidance; and a September 2025 sub-award from Clemson University focused on emergency medicine clinician well-being and scheduling optimization, with Prisma Health providing clinical staff access, shift-schedule review, and HIPAA-compliant data extraction and analytics support led by emergency medicine physicians Ronald Pirrallo and Emily Hirsh.

All three awards route through the Department of Health and Human Services — the Centers for Disease Control and Prevention, the National Institutes of Health National Institute of General Medical Sciences, and the NIH Office of the Director — with combined dollars obligated of $405 thousand across a two-year window (2025–2026). The vendor's federal activity is nascent: one award in 2025 and two awards in 2026, with all work positioned as a clinical-research-support sub-recipient to universities holding the prime grant instruments. Prisma Health does not appear on federal contracts, GWACs, GSA Schedules, or agency-wide IDIQs in the source data.