Trestle Optics LLC

Trestle Optics LLC is a small disadvantaged business registered in SAM.gov located in Irvine, California, operating as a sole proprietorship focused on advanced microscopy and optical technology development. The company specializes in innovative optical engineering and biomedical research technology, with a particular emphasis on developing cutting-edge microscopy systems and imaging techniques that enable high-resolution chemical and metabolic analysis at the cellular level. Their technological focus appears centered on developing advanced optical platforms that can non-destructively image and analyze cellular metabolites using sophisticated techniques like photothermal microscopy, spatial light interference imaging, and broadband optical systems.

Trestle Optics LLC has received multiple federal grants from agencies including the National Institute of General Medical Sciences (NIGMS), National Science Foundation (NSF), and Department of Energy's Office of Science, primarily targeting biomedical research and technological innovation. Their grant-funded projects have consistently focused on developing novel microscopy technologies for metabolite profiling, including a $330,076 project to create a photothermal microscopy platform for non-destructively monitoring metabolites in individual cells, a $305,647 grant to develop a microfluidic platform for screening and sorting microalgae, and a $290,536 project to design an ultra-broadband catadioptric lens for multimodal microscopy. These projects demonstrate the company's expertise in creating advanced optical systems for synthetic biology, preclinical drug development, and metabolomic research, with applications ranging from identifying high-producing microalgae strains to developing new tools for chemical imaging and cell screening across various scientific domains.