Research Foundation For Mental Hygiene, Inc.

Research Foundation For Mental Hygiene, Inc., operating through its New York State Psychiatric Institute Division (doing business as New York Psychiatric Center), is a tax-exempt nonprofit research organization headquartered in Menands, New York, that acts as a recipient of federal research grants across mental health, neuroscience, substance use, and aging research. The organization does not hold federal contracts; its federal footprint is entirely composed of project grants, cooperative agreements, and sub-recipient positions within larger research awards. The portfolio shows no set-aside activity and no service-contract-reportable revenue.

The vendor's concrete federal role centers on conducting clinical research, epidemiological studies, and basic neuroscience research on behalf of the National Institutes of Health. Representative work includes a $1.248 million NIMH project testing evidence-based early intervention services for psychosis in Mozambique (MWELL-CSC), a $818,498 NIMH project investigating hippocampal gene expression in depression using postmortem brain tissue and longitudinal cohort data from 11,700 adolescents, a $1.844 million NIMH treatment optimization study in anorexia nervosa using the Multiphase Optimization Strategy framework across 120 individuals, and a $3.295 million NIMH project examining stress response, suicide behavior, and ketamine's preventive impact in high-risk depressed patients. Across substance use research, the recipient manages a $1.248 million National Institute on Drug Abuse study of cannabis effects on nicotine use, a $450,175 NIDA project testing sphenopalatine ganglion blocks for opioid use disorder, and a $717,986 NIDA cooperative agreement on transcutaneous auricular neurostimulation for naloxone-precipitated withdrawal. Grant awards typically fund five-year project periods with performance at sites in New York (primarily New York City) and select international locations (Mozambique, Uganda, Guyana).

Customer concentration is extreme and reflects NIH's research mission. The National Institute of Mental Health accounts for 193 awards (30% of all awards in source data); NIDA accounts for 114 awards with $39.4 million combined potential value; the National Institute on Aging accounts for 36 awards; and the National Institute on Alcohol Abuse and Alcoholism accounts for 17 awards. Together, these four NIH institutes and the parent National Institutes of Health body represent 82% of all awards and 95% of combined potential value. The vendor serves 37 federal agencies total, but the remaining 18% of awards are scattered among HHS programs (National Heart Lung and Blood Institute, Fogarty International Center, NIDILRR), the Defense Health Agency, the National Science Foundation, and the National Human Genome Research Institute.

Activity has remained steady across recent years, with 40 awards in FY2022, 34 in FY2023, 56 in FY2024, 36 in FY2025, and 41 through September 2026. Eighty-three awards are scheduled to reach ultimate completion within the next twenty-four months, representing a recompete cliff of unknown aggregate dollar value (source data flag combined potential value across all awards at $41.4 million but obligated dollars at $1.51 billion, suggesting the portfolio is dominated by renewal and continuation awards with large prior-year obligations). The Service Contract Inventory dataset shows no federal service-contract revenue reported for the vendor as a prime contractor across FY2022–FY2025; the vendor appears twice in the SCI subcontractor population with negligible FTE (<1 FTE across both records), indicating minimal participation in reportable federal service contracting outside the grant environment.

The vendor's federal grant role is almost entirely as a prime recipient; 530 of 652 awards (81%) are prime grants or sub-recipients of prime grants, while 122 (19%) are sub-awards under other prime recipients. Subcontracts position the vendor under Columbia University (frequent collaborator), Yale, New York University, Rutgers, Duke, University of Pittsburgh, Long Island Jewish Medical Center, and University of Wisconsin. The corporate structure confirms the child-entity relationship: the Division (New York State Psychiatric Institute) operates under the parent Research Foundation For Mental Hygiene Inc., which maintains the federal relationship.

The vendor's research model emphasizes collaborative, multisite studies with robust data-collection infrastructure and specialized expertise in neuroimaging (PET, fMRI, neuromelanin-sensitive MRI), electrophysiology, genomics, mitochondrial phenotyping, and psychiatric epidemiology. Work spans human clinical trials, animal models, postmortem brain tissue analysis, real-world observational studies, and implementation science. Performance geography extends from the New York metro area to international low- and middle-income settings. The recipient does not compete for contracts or set-aside procurement; all federal funding flows through the NIH grant mechanism, with NIMH and NIDA as the primary funding sources and NYSPI/RFMH positioned as either lead site or research-delivery partner in networks anchored by Columbia University and other major academic medical centers.