Reaction Biology Corporation
Malvern, PA
- UEI
- LDBCLKM4WJH1
- CAGE
- 486T0
- Primary NAICS
- 541380 Testing Laboratories and Services
- SAM.gov registration
- Active through
Company facts
- Self-certified in SAM.gov
- Entity structure
- Corporate Entity (Not Tax Exempt)
- NAICS codes registered in SAM.gov
- SAM.gov registration date
- Physical address
- 1 Great Valley Pkwy #2, Malvern, PA 19355, USA
- Website
- reactionbiology.com
- Founded
- 2001
- Employees
- 51-250
- Estimated annual revenue
- $10M-$50M
- Industry
-
- Industrials
- Commercial & Professional Services
- Professional Services
- SIC code
- 87 Engineering & Management Services
Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .
Recent federal awards
| Award | Agency | Obligated | Awarded |
|---|---|---|---|
| Bioactive small molecule development project - gamma 33P ATP kinase assay and nanobret kinase assay | Interior Business Center | $59,768 | |
| Biochemical kinase assays, 160 compounds | National Center for Advancing Translational Sciences | $19,840 | |
| Testing of 2 compounds against the the selected kinase panel in a biochemical gamma 33P- ATP kinase assay | National Center for Advancing Translational Sciences | $21,028 | |
| Gamma 33P ATP kinase assay and nanobret kinase assay testing | National Institute on Drug Abuse | $100,560 | |
| Reaction biology corporation:1186704 [24-000909] | National Institute on Drug Abuse | $11,304 |
About Reaction Biology Corporation
Reaction Biology Corporation is a self-certified small disadvantaged business and contract research organization headquartered in Malvern, Pennsylvania, with additional laboratory facilities in Maryland. The company specializes in providing advanced biochemical and preclinical research services to support translational science initiatives across the National Institutes of Health and its various institutes and centers. Reaction Biology has established itself as a key provider of enzyme activity assays, screening services, and related laboratory testing that enables biomedical researchers to characterize potential therapeutic compounds and elucidate drug mechanisms of action. The company operates proprietary screening platforms including Kinase HotSpot and Methyltransferase HotSpot assays that facilitate comprehensive enzymatic testing for novel small molecules and other drug candidates.
Reaction Biology Corporation has received a consistent stream of firm fixed-price purchase order contracts from the National Center for Advancing Translational Sciences (NCATS), the National Institute on Drug Abuse (NIDA), and the Office of Logistics and Acquisition Operations, with contract values ranging from $11,304 to $166,500. The company's federal contract work has primarily involved kinase inhibition testing and profiling services, including Gamma 33P ATP kinase assays and NanoBRET kinase assays conducted across varying numbers of wild-type kinase panels and novel small molecule compounds. Notable projects include testing 370 wild-type kinase enzymes, screening 377 kinases against 10 compounds, profiling 10 BTK inhibitors versus a 20-kinase panel, and characterizing dose-response relationships for hundreds of test compounds. In addition to kinase assays, Reaction Biology has provided methyltransferase panel screening services using its proprietary Methyltransferase HotSpot platform, cell profiling services, and cellular NanoBRET assays to support cancer research, COVID-19 research initiatives, and other translational science projects. All contracts were awarded without small business set-aside designations, with many structured as sole-source awards justified by the requirement for data consistency, methodology continuity, and the company's specialized technical capabilities in maintaining comparable sample analysis throughout ongoing research projects.
Quick answers
What is Reaction Biology Corporation's UEI?
Reaction Biology Corporation's Unique Entity ID (UEI) in SAM.gov is LDBCLKM4WJH1.
What is Reaction Biology Corporation's CAGE code?
Reaction Biology Corporation's CAGE code is 486T0.
What is Reaction Biology Corporation's primary NAICS code?
Reaction Biology Corporation's primary NAICS code is 541380 (Testing Laboratories and Services).
Where is Reaction Biology Corporation located?
Reaction Biology Corporation's physical address in SAM.gov is 1 Great Valley Pkwy #2, Malvern, PA 19355, USA.
Is Reaction Biology Corporation registered in SAM.gov?
Yes. Reaction Biology Corporation's SAM.gov registration is active through March 2, 2027.
What is Reaction Biology Corporation's most recent federal award?
Reaction Biology Corporation's most recent federal contract award is Bioactive small molecule development project - gamma 33P ATP kinase assay and nanobret kinase assay (140D0425P0049), from Interior Business Center, on September 19, 2025.
On GovTribe
See Reaction Biology Corporation's full federal record
- Federal contract awards
- Federal grant awards
- Funding analysis by agency, NAICS and set-aside
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