Nucleic Sensing Systems LLC
Saint Paul, MN
- UEI
- SPQPZK9BUYR3
- CAGE
- 8NHM6
- Primary NAICS
- 334516 Analytical Laboratory Instrument Manufacturing
- SAM.gov registration
- Active through
Company facts
- Self-certified in SAM.gov
- Entity structure
- Partnership or Limited Liability Partnership
- Other NAICS codes in SAM.gov
- SAM.gov registration date
- Physical address
- 1865 Ashland Ave, St Paul, MN 55104, USA
- Website
- ns2co.com
- Founded
- 2020
- Employees
- 1-10
- Estimated annual revenue
- $0-$1M
- Industry
-
- Industrials
- Commercial & Professional Services
- Professional Services
- SIC code
- 87 Engineering & Management Services
- Profiles
Registration and certifications come from SAM.gov and the SBA; company details from public web sources. Updated .
Contract obligations by fiscal year
| Fiscal year | Obligated |
|---|---|
| FY2027 To date | $0 |
| FY2026 | $342,718 |
| FY2025 | $0 |
| FY2024 | $177,570 |
Top agencies by obligations
| Rank | Agency | Obligated, FY2026–FY2027 | Share |
|---|---|---|---|
| 1 | Department of Commerce | $342,718 |
Contract awards
Grant awards
Grant subawards
| Prime recipient | Prime award | Amount | Awarded |
|---|---|---|---|
| National Collegiate Inventors & Innovators Alliance, Inc. | NA25NOSX012C0014 | $50,000 |
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About the company
Nucleic Sensing Systems LLC, a for-profit limited liability company based in St. Paul, Minnesota, develops autonomous biosensing instruments for environmental DNA (eDNA) detection and aquaculture disease monitoring, operating as a prime contractor and grant recipient on small-business federal work with no set-aside designation across recent awards.
The vendor specializes in real-time environmental monitoring systems capable of detecting genetic material in field conditions and transmitting data remotely to federal researchers. Nucleic Sensing Systems operates primarily under the SBIR/STTR program pathway, competing full-and-open rather than under any set-aside vehicle. The company's capability footprint centers on automated analyzer design, biosensor development, and autonomous detection systems. Representative work includes a $342,718 firm fixed-price purchase order from NOAA (awarded July 2, 2026, ultimate completion February 19, 2027) for engineering support and development of an eDNA automated analyzer; a $177,570 SBIR Phase III action from NOAA (awarded August 19, 2024) to develop an automated eDNA analyzer for detection of free environmental DNA in field conditions with real-time remote monitoring of target species; and a $175,000 SBIR/STTR grant from the Department of Agriculture's National Institute of Food and Agriculture (CFDA 10.212, awarded July 1, 2022) for development of autonomous biosensing technologies to monitor viral pathogens in aquaculture, including assembly and validation of a benchtop detection submodule for three target viral pathogens (infectious hematopoietic necrosis virus, viral hemorrhagic septicemia virus, infectious pancreatic necrosis virus) and professional engineering design of an alpha product unit suitable for production.
Customer concentration is extreme: the National Oceanic and Atmospheric Administration accounts for three awards totaling $520 thousand (85% of combined potential value), with the U.S. Geological Survey and the Department of Agriculture rounding out the active base. The vendor holds 80% of recent awards as a prime contractor or grant recipient, with one sub-award role as a participant in a National Collegiate Inventors & Innovators Alliance technology development and commercialization program (awarded January 21, 2026). Activity remains sparse but recent — two awards each in 2022 and 2026, with one award in 2024 — and one award (the most recent NOAA purchase order valued at $343 thousand) faces completion within the next twenty-four months.
SBA capabilities narrative
Research and development around environmental DNA technologies. Environmental DNA autonomous in-field testing.
Quick answers
Is Nucleic Sensing Systems LLC registered in SAM.gov?
Yes. Nucleic Sensing Systems LLC's SAM.gov registration is active through January 12, 2027.
What is Nucleic Sensing Systems LLC's CAGE code?
Nucleic Sensing Systems LLC's CAGE code is 8NHM6, and its Unique Entity ID (UEI) is SPQPZK9BUYR3.
How much has Nucleic Sensing Systems LLC received in federal contracts?
Federal contracts obligated $520,288 to Nucleic Sensing Systems LLC in fiscal years 2023 through 2027.
What is Nucleic Sensing Systems LLC's most recent federal award?
Nucleic Sensing Systems LLC's most recent federal contract award is Engineering support and development of an environmental DNA (EDNA) automated analyzer (1305M326P0134), from National Oceanic and Atmospheric Administration, on July 2, 2026.
On GovTribe
See Nucleic Sensing Systems LLC's full federal record
- Federal contract awards
- Federal grant awards
- Funding analysis by agency, NAICS and set-aside
- Similar vendors