Double Helix Optics, Inc.

Double Helix Optics, Inc. is a for-profit organization and manufacturer of goods that specializes in the design and development of advanced optical systems and technologies. Founded in 2011, the company holds exclusive licensing rights to Light Engineering Technology from the University of Colorado and Stanford University, positioning it as a leader in 3D imaging solutions.

Through prime federal grant awards from agencies like the National Institutes of Health (NIH), Double Helix Optics has developed groundbreaking products and technologies for biomedical research and spatial omics applications. Notably, the company has received grants to design engineered point spread function (EPSF) objective lenses and matched computational algorithms for spatial omics research, enabling faster data capture, increased sample labeling density, reduced dataset size, and decreased phototoxicity. Additionally, Double Helix Optics has developed a multidimensional multifunctional quantitative optical microscopy modular system for live whole-cell studies, featuring engineered 3D light excitation, extended depth of field imaging, high-sensitivity 3D localization, multi-color imaging, and real-time experiment control software. These innovations, funded through programs like the Small Business Innovation Research (SBIR) and the Biomedical Research and Research Training program, aim to advance fields such as oncogenesis, degenerative disease research, stem cell biology, cancer research, and brain research.