Cyagen Biomodels LLC

Cyagen Biomodels LLC is a for-profit biotechnology company based in Santa Clara, California, specializing in advanced genetic research services and animal model development. Registered in SAM.gov since August 11, 2021, the company provides sophisticated genetic engineering solutions to federal research agencies, with a primary focus on creating customized mouse models for scientific investigations. The company's core competency lies in generating genetically engineered mouse models through techniques like conditional knockin, knockout, and gene targeting, which support advanced biomedical research across multiple scientific domains.

The federal contract awards reveal that Cyagen Biomodels LLC has consistently worked with agencies such as the National Institutes of Health (NIH), including the National Institute of Child Health and Human Development, National Cancer Institute, National Institute on Aging, and National Institute of Allergy and Infectious Diseases, as well as the U.S. Department of Agriculture (USDA) and Department of Veterans Affairs. Their contracts, predominantly firm fixed-price purchase orders ranging from $11,749 to $275,922, involve highly specialized services like generating gene-targeted mouse models for studying prion diseases, investigating protein functions, developing conditional knockout mouse strains, and performing whole genome and RNA sequencing. Most contracts were not set aside for small businesses, though one USDA contract was a total small business set-aside. The company's work supports critical research in areas including bone metabolism, infectious diseases, hematopoietic system development, and understanding various genetic mechanisms across multiple biological systems.