Sexually Transmitted Diseases (STD) Prevention and Control Grants

Active

Assistance listing
93.977
Agency
Grant awards
506 $2,882,582,060 in federal obligations

Program facts

Also known as
STD Prevention
Assistance types
  • Cooperative Agreement
  • Project Grant
  • Block Grant
Treasury account
  • 75-0950-0-1-550
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The CDC's Centers for Disease Control and Prevention is providing project and cooperative agreement grants totaling $2.88 billion since 1990 to state and local health departments, academic institutions, and public health organizations to strengthen sexually transmitted infection (STI) prevention and control programs, with the most recent award made in January 2025 under CFDA 93.977.

The program funds surveillance activities including reporting, screening, and follow-up of STI cases; disease intervention to locate cases and notify and refer exposed partners to care; development and implementation of nationally uniform prevention and control programs emphasizing assessment, assurance, and policy development; and community-based interventions targeting populations disproportionately burdened by chlamydia, gonorrhea, syphilis, and congenital syphilis. Recent funded activities span STI surveillance network projects integrating HIV, mpox, and behavioral data collection in sexual health clinics; enhanced case-based surveillance in defined geographic areas; bioethics and public health ethics education focused on underserved communities; and community-led approaches to address social determinants of health driving STI transmission in priority populations including men who have sex with men, transgender individuals, adolescents and young adults, pregnant women, and people experiencing homelessness.

Awards are predominantly Project Grants (67 percent) with substantial shares of Cooperative Agreements (19 percent) and Block Grants (14 percent). CDC dominates funding across all five documented funder breakdowns in the portfolio, collectively obligating $961.6 million, $818.6 million, $635.1 million, $435.2 million, and $16.6 million across distinct funding lines. Recent annual award cadence shows variability—one award in 2021 and 2022, 16 in 2023, 13 in 2024, and one in 2025—suggesting program activity resumed at higher levels after a 2021–2022 lull. Combined federal and non-federal obligated dollars total $2.89 billion, with a negligible cost-share component. Representative recent awards include CDC STI Surveillance Network (SSuN) Cycle 5 cooperative agreements in California ($1.748 million), Colorado ($1.210 million), New York City ($1.001 million), and Washington State ($922 thousand); Florida's High-Impact HIV Prevention and Surveillance Programs cooperative agreement ($207.881 million); Brazil HIV and other infectious diseases prevention cooperative agreement ($10.228 million); and community-based STI reduction initiatives in Los Angeles, Philadelphia, and San Francisco ranging from $936 thousand to $2.463 million.

The program currently has an open opportunity: CDC-RFA-PS-27-0008, Controlling and Preventing STIs in US Health Departments (CAP-STIs), posted May 11, 2026, supporting cooperative agreements for state, district, territorial, city, and county health departments to track, prevent, and control syphilis, gonorrhea, and chlamydia. All fifty states, D.C., Puerto Rico, and the U.S. Virgin Islands are eligible for non-competitive formula-based funding; a limited number of directly funded cities may compete based on population, STI morbidity, and organizational capacity.

Objective and description

Objective

The purpose of the assistance is to strengthen STD prevention programs in eligible jurisdictions. Project grants awarded under Section 318 to State and local health departments, academic and public health organizations emphasize the development and i

Description

The purpose of the assistance is to strengthen STD prevention programs. Project grants awarded under Section 318 to State and local health departments, academic and public health organizations emphasize the development and implementation of nationally uniform prevention and control programs which focus on the core public health functions of assessment, assurance, policy development, and prevention services. This includes surveillance activities, including the reporting, screening, and follow up of persons diagnosed with STDs, and disease intervention activities to find cases, and notify and refer exposed partners to STD into care.

Eligibility

Applicant eligibility

Any State, and, in consultation with the appropriate State Health Authority, any political subdivision of a State, including American Indian/Alaska Native tribal governments or tribal organizations located wholly or in part within their boundaries; academic institutions and national and public health organizations.

Beneficiary eligibility

Any State or authorized subdivision including American Indian/Alaska Native tribal governments or tribal organizations located wholly or in part within their boundaries, academic institutions and public health organizations.

Uses of assistance

Grant funds may be used for: (1) STD surveillance activities, including reporting, and follow-up of diagnostic tests for, and diagnosed cases of, STD; (2) STD case finding and case follow-up activities, including notification, referral and follow up of sex partners for STD testing and treatment, as appropriate; (3) interstate epidemiological referral and follow-up activities; (4) program-specific professional (including appropriate allied health personnel) STD education and training as authorized under section 318 of the PHS Act; (5) program-specific and public STD education and information dissemination as authorized under Section 318 of the PHS Act; (6) applied research, special studies or demonstrations to evaluate or test STD prevention and control activities; and (7) other control strategies and activities as may be prescribed by the Secretary.

Length and time phasing of assistance

Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.

How to apply

Criteria for selecting proposals

Applications will be evaluated based upon the magnitude of the problem, the establishment of specific and measurable objectives to address the problem, and the development of a sound operational plan which will ensure the implementation of each program element.

Award procedure

After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public. Initial awards provide funds for the first budget period (usually 12 months) and the NoA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, award requirements, and special conditions, if any.

Renewals

Project period of performance is 1 to 5 years. After initial awards, and subject to availability of funds, projects may be continued non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.

Grant opportunities

Opportunity Status Posted Applications due
Controlling and Preventing STIs in US Health Departments (CAP-STIs) CDC-RFA-PS-27-0008 Forecasted —
Sexually Transmitted Infections (STI) Surveillance Network (SSuN) Cycle 5 CDC-RFA-PS-24-0082 Closed
Support and Scale Up of HIV Prevention Services in Sexual Health Clinics CDC-RFA-PS-24-0003 Closed
Community-Based Approaches to Reducing Sexually Transmitted Diseases (CARS) CDC-RFA-PS23-2306 Closed
Enhancing STI and Sexual Health Clinic Infrastructure (ESSHCI) CDC-RFA-PS-23-0011 Closed
Support Technical Assistance & Opportunities for Program, Policy, & Communications to Prevent STDs (STOP STDs) CDC-RFA-PS-23-0007 Closed
Support and Scale Up of HIV Prevention Services in Sexual Health Clinics CDC-RFA-PS22-2212 Past —
Prevention Research Network to Support Population-level Prevention of COVID-19 and Other Infectious Diseases Through Disease Intervention Services RFA-PS-22-003 Past —
National Center for HIV-AIDS, Viral Hepatitis, STD, and TB Prevention CDC-RFA-PS19-1907 Closed
Strengthening STD Prevention and Control for Health Departments (STD PCHD) CDC-RFA-PS19-1901 Closed
STD AAPPS Supplemental Funding for Enhanced Congenital Syphilis Response CDC-RFA-PS14-14020401SUPP17 Closed
Evaluation of STD Programs' Deployment of DIS to Improve HIV Outcomes CDC-RFA-PS15-151103CONT17 Closed
STD Surveillance Network (SSuN) CDC-RFA-PS13-130605CONT17 Closed
National Network of Sexually Transmitted Diseases CDC-RFA-PS14-140703CONT16 Closed
STD/HIV Disease Intervention Services Training Centers (DISTC) CDC-RFA-PS14-140803CONT16 Closed
Evaluation of STD Programs Deploying Disease Intervention Specialist (DIS) to Improve Human Immunodeficiency Virus (HIV) Outcomes CDC-RFA-PS15-1511 Closed
National Network to Enhance Capacity of State and Local Sexually Transmitted Disease Prevention Programs (NNECS) CDC-RFA-PS13-130903CONT15 Closed
Initiatives to Educate State Officials and Policy Makers about Priority Public Health Issues Related to the Prevention and Control of STDs and HIV/AIDS, NCHHSTP CDC-RFA-PS11-111802CONT12 Closed
Initiatives to Educate State Officials and Policy Makers about Priority Public Health Issues Related to the Prevention and Control of Sexually Transmitted Diseases (STDs) and Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) CDC-RFA-PS11-1118 Closed
Comprehensive STD Prevention Systems-Infertility Prevention Project CDC-RFA-PS09-9020301SUPP11 Closed
Show all 20

Grant awards

Award Recipient Federal obligations Awarded
Comprehensive effort in bioethics, public health ethics, and social justice education, with a focus on underserved… NU22PS004717 Tuskegee University $640,000
Fiotec - fundacao para o desenvolvimento cientifico e tecnol NU2GGH002515 Fiotec - Fundacao Para O Desenvolvimento Cientifico E Tecnologico Em Saude $10,228,152
Sexually transmitted infections (STI) surveillance network (ssun) cycle 5 NH25PS005268 Washington State Department Of Health $922,220
STI surveillance network (ssun) cycle 5 NH25PS005267 City Of Philadelphia $781,480
STD surveillance network - chlamydia (CT), gonorrhea (GC), and syphilis are nationally reportable curable bacterial… NH25PS005266 Florida Department Of Health $362,031
Sexually transmitted infections (STI) surveillance network (ssun) cycle 5 - the sexually transmitted infections (STI)… NH25PS005265 City Of New York $1,001,480
SAN francisco STI surveillance network (ssun) project NH25PS005262 City & County Of San Francisco $960,000
Columbus public health is partnering with the ohio department of health (ODH), ohio state university (OSU) and CDC to… NH25PS005261 City Of Columbus $943,013
Sexually transmitted infection surveillance network (ssun) NH25PS005260 California Department Of Public Health $1,748,600
The application is in support of sentinel and enhanced surveillance for stis by improving demographic, behavioral… NH25PS005256 District Of Columbia, Government Of $704,460

Latest 10 of 506 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 128 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $41,843,611
FY2025 $47,600,499
FY2024 $168,890,615
FY2023 $906,812,124
FY2022 $766,839,409
FY2021 $298,731,910
FY2020 $218,892,385
FY2019 $108,581,596
FY2018 $93,251,180
FY2017 $103,409,064
FY2016 $105,709,298
FY2015 $105,659,451
FY2014 $104,825,880
FY2013 $98,997,801
FY2012 $104,325,109
FY2011 $105,066,190
FY2010 $103,198,779
FY2009 $106,542,249
FY2008 $101,810,124
FY2007 $3,033,913
FY2006 $35,744,516
FY2005 $524,035
FY2004 $2,675,242
FY2003 $1,188,212
FY2002 $20,000
Show all 25

Quick answers

What is Assistance Listing 93.977?

Assistance Listing 93.977 is Sexually Transmitted Diseases (STD) Prevention and Control Grants, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).

What is the CFDA number for Sexually Transmitted Diseases (STD) Prevention and Control Grants?

Its CFDA number is 93.977: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.977 awarded?

506 grant awards under 93.977 have obligated $2,882,582,060 in federal funds to 128 recipients.

Who receives the most funding from 93.977?

The recipients obligated the most under Sexually Transmitted Diseases (STD) Prevention and Control Grants are Florida Department Of Health ($441,604,250), California Department Of Public Health ($280,446,067) and Department Of State Health Services ($252,698,314).

How much did 93.977 obligate in fiscal year 2025?

Grants under 93.977 obligated $47,600,499 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.977?

1 listed opportunity under 93.977 is open or forecasted. The latest, Controlling and Preventing STIs in US Health Departments (CAP-STIs), was posted on May 11, 2026.

On GovTribe

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