Special Projects of National Significance
Active
- Assistance listing
- 93.928
- Agency
-
Health Resources and Services Administration
Department of Health and Human Services
- Grant awards
- 528 $478,274,284 in federal obligations
Program facts
- Also known as
- SPNS
- Assistance types
-
- Project Grant
- Block Grant
- Treasury account
-
- 75-0350-0-1-550
- More information
Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.
About this program
The Department of Health and Human Services Health Resources and Services Administration funds demonstration, implementation, and evaluation projects that develop and test innovative HIV care and treatment models under the Ryan White HIV/AIDS Program Part F Special Projects of National Significance (SPNS) program, CFDA 93.928, with the most recent grant award disbursed on September 1, 2026.
The program funds concrete implementation science projects: demonstration sites that pilot emerging interventions for specific populations (men with HIV out of care, people aging with HIV, unsheltered individuals, those with co-occurring mental health conditions); implementation technical assistance providers that build capacity and support sites in adapting evidence-informed interventions; and evaluation providers that conduct multi-site assessments of implementation processes and health outcomes. Recent awards reflect this focus—a September 2026 implementation technical assistance award of $3.24 million to support men's HIV engagement and retention across eight sites nationwide; a $13.6 million dissemination assistance award in August 2024 to promote eligibility streamlining across Ryan White program parts; and a $25.05 million evaluation award in September 2023 to assess status-neutral HIV prevention approaches for racial and ethnic minorities.
The program remains active and well-resourced. Over 528 awards totaling $478.3 million in federal obligations have been disbursed since 1999, with annual award volume ranging from 2 to 15 awards in recent years (2 awards in 2026 through early September, 14 in 2025, 8 in 2024). Project Grants comprise 89 percent of awards, with Block Grants making up the remaining 11 percent. The portfolio reflects volatile funding concentration: one funder (Health Resources and Services Administration) accounts for both 430 awards at $116.9 million and 98 awards at $361.4 million, indicating data reporting of distinct funding tracks or initiative cohorts rather than competing funders.
Three actively solicited opportunities close July 2026: HRSA-26-101 (Supporting Interventions with Technical Assistance, posted March 23, 2026) seeks one organization to deliver tailored implementation support to up to 20 Ryan White sites addressing barriers to intervention adoption; HRSA-26-088 (Strategies to Link, Engage, and Retain Men with HIV in Care: Implementation Technical Assistance Provider, posted February 26) funds one cooperative agreement to manage up to eight male-focused implementation sites; and HRSA-26-087 (the companion Evaluation Provider, posted February 26) funds one cooperative agreement for multi-site evaluation across the same men's initiative.
Objective and description
- Objective
The purpose of the Ryan White HIV/AIDS Program (RWHAP) Part F Special Projects of National Significance (SPNS) Program is to support the development of innovative models of HIV care and treatment to quickly respond to emerging needs of RWHAP clients.
- Description
The purpose of the Ryan White HIV/AIDS Program (RWHAP) Part F Special Projects of National Significance (SPNS) Program is to support the development of innovative models of HIV care and treatment to quickly respond to emerging needs of RWHAP clients. Through its demonstration, implementation, and health information technology projects, SPNS uses implementation science to evaluate the design, implementation, use, cost, and health-related outcomes of treatment strategies while promoting the dissemination and replication of successful interventions in the RWHAP. This unique program advances knowledge and skills in the delivery of health care, support services, and data integration to serve RWHAP priority populations. Through these special projects, RWHAP SPNS recipients implement a variety of interventions that advance public health knowledge and help to achieve the goal of ending the HIV epidemic in the United States.
Eligibility
- Applicant eligibility
Academic institutions, non-profit organizations including faith-based organizations, and those eligible for funding under Parts A-D authorized by Title XXVI of the Public Health Service (PHS) Act. Additionally, federally recognized Indian Tribal Governments and tribal organizations are also eligible to apply for these funds.
- Beneficiary eligibility
Individuals with HIV.
- Uses of assistance
Proposals are expected to adequately define and justify the needs, innovative nature, and evaluation methodology of the proposed model of services. Funds shall be used to create and/or evaluate innovative models of HIV care, services, capacity development initiatives, and health information and technology data systems that would likely not exist nor be evaluated without RWHAP Part F SPNS Program support, or that would extend the care model to previously underserved or uninsured populations.
- Use restrictions
Funds may not be used for: • charges that are billable to third party payers (e.g., private health insurance, prepaid health plans, Medicaid, Medicare); • purchasing or construction of new facilities or capital improvements to existing facilities; • purchasing or improving land; • international travel; • cash payments to intended recipients of RWHAP services; • pre-exposure prophylaxis (PrEP); • non-occupational post-exposure prophylaxis (nPEP) Funds may not be used for outreach programs that have HIV prevention education as their exclusive purpose, or broad-scope awareness activities about HIV services that target the general public. Additionally, the purchase of sterile needles or syringes for the purposes of hypodermic injection of any illegal drug is not allowable. Some aspects of syringe services programs are allowable with HRSA's prior approval and in compliance with HHS and HRSA policy (see: https://www.hiv.gov/federal-response/policies-issues/syringe-services-programs).
- Length and time phasing of assistance
Grants and cooperative agreements will generally be awarded for project periods ranging from two to five years. Budget periods are composed of up to two to five 12-month budget periods depending on the focus area, implementation and replication activities, evaluation framework, and dissemination plan timelines.
How to apply
- Criteria for selecting proposals
Evaluation criteria vary and are based on the initiative. Refer to criteria included in the notice of funding opportunity (NOFO) for each specific program.
- Award procedure
All qualified applications will be forwarded to an objective review committee. Based on the recommendations of the objective review committee, the HRSA program official with delegated authority is responsible for final selection and funding decisions. Notification is made in writing by a Notice of Award (NOA).
- Time to approval or disapproval
Approximately 6 months.
- Renewals
Competitive awards are typically made for up to 2 to 5 years, subject to the availability of funds. After initial awards, annual noncompetitive awards may be made contingent upon the submission of noncompetitive applications/progress reports, availability of funds and a determination that continued funding would be in the best interest of the federal government.
Grant opportunities
Show all 40
Grant awards
Latest 10 of 528 listed here. See the rest on GovTribe.
Top recipients by federal obligations
| Rank | Recipient | Federal obligations | Share |
|---|---|---|---|
| 1 | JSI Research & Training Institute Inc. | $69,916,714 | 15% |
| 2 | Fenway Community Health Center, Inc. | $55,499,187 | 12% |
| 3 | National Alliance Of State & Territorial Aids Directors | $37,407,545 | 8% |
| 4 | Corporation For Supportive Housing | $36,213,808 | 8% |
| 5 | The Regents Of The University Of California. San Francisco | $26,686,008 | 6% |
| 6 | Yale Univ | $10,698,867 | 2% |
| 7 | National Opinion Research Center | $8,736,320 | 2% |
| 8 | The University Of North Texas Health Science Center At Fort Worth | $8,500,000 | 2% |
| 9 | Trustees Of Boston University | $7,889,998 | 2% |
| 10 | Health Research, Inc. | $6,625,222 | 1% |
10 of 239 recipients listed here. See the rest on GovTribe.
Federal obligations by fiscal year
| Fiscal year | Federal obligations |
|---|---|
| FY2026 | $14,676,552 |
| FY2025 | $54,762,158 |
| FY2024 | $55,009,642 |
| FY2023 | $53,623,444 |
| FY2022 | $44,451,324 |
| FY2021 | $19,572,938 |
| FY2014 | -$6,501 |
| FY2013 | $23,047,928 |
| FY2012 | $23,994,591 |
| FY2011 | $21,561,360 |
| FY2010 | $23,268,578 |
| FY2009 | $23,729,640 |
| FY2008 | $2,334,836 |
| FY2007 | $20,630,942 |
| FY2006 | $200,000 |
| FY2005 | $8,217,464 |
| FY2004 | $310,000 |
| FY2003 | $14,865,360 |
| FY2002 | $22,801,133 |
| FY2001 | $12,774,126 |
Show all 20
Quick answers
What is Assistance Listing 93.928?
Assistance Listing 93.928 is Special Projects of National Significance, a federal grant program run by Health Resources and Services Administration (Department of Health and Human Services).
What is the CFDA number for Special Projects of National Significance?
Its CFDA number is 93.928: Assistance Listing numbers were called CFDA numbers before 2018.
How much funding has Assistance Listing 93.928 awarded?
528 grant awards under 93.928 have obligated $478,274,284 in federal funds to 239 recipients.
Who receives the most funding from 93.928?
The recipients obligated the most under Special Projects of National Significance are JSI Research & Training Institute Inc. ($69,916,714), Fenway Community Health Center, Inc. ($55,499,187) and National Alliance Of State & Territorial Aids Directors ($37,407,545).
How much did 93.928 obligate in fiscal year 2025?
Grants under 93.928 obligated $54,762,158 in federal funds in fiscal year 2025.
Are there open grant opportunities under 93.928?
No opportunity listed under 93.928 is open now. The latest, Supporting Interventions with Technical Assistance, was posted on March 23, 2026.
On GovTribe
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