Sickle Cell Treatment Demonstration Program

Active

Assistance listing
93.365
Agency
Grant awards
22 $112,548,307 in federal obligations

Program facts

Also known as
SCDTDP
Assistance types
  • Project Grant
  • Cooperative Agreement
Treasury account
  • 75-0354-0-1-550
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Department of Health and Human Services Health Resources and Services Administration operates the Sickle Cell Treatment Demonstration Program (CFDA 93.365) to fund systemic improvements in sickle cell disease prevention and treatment, with the most recent grant award made on September 1, 2021, and an active opportunity due July 8, 2026.

The program funds development of coordinated care delivery systems for sickle cell disease patients, including genetic counseling and testing, training of health professionals, and expansion of education and continuity-of-care services. Recent awards have supported regional coordinating hubs and networks providing telementoring, telemedicine, and evidence-based clinical support across multiple geographic regions to increase provider capacity and improve access to quality care. Competitive awards are typically made for two to five years, subject to fund availability, with potential for subsequent noncompetitive renewals contingent on progress reports and continued federal interest. Final funding decisions are made four to six months after application receipt.

The program is predominantly Cooperative Agreements, which constitute 73 percent of the 22 historical awards, with Project Grants comprising the remaining 27 percent. All funding has come from the Department of Health and Human Services Health Resources and Services Administration across two distinct award mechanisms: one mechanism has supported 16 awards totaling $34.7 million federal dollars obligated, while the other has supported 6 awards totaling $77.9 million federal dollars obligated, for a combined program total of $112.5 million obligated since 2006.

Recent award magnitudes vary substantially. Representative recent awards include a Project Grant of $15.2 million (September 2021, completion August 2027); a Project Grant of $21.1 million (September 2014, completion August 2026); and a Cooperative Agreement of $4.6 million (September 2014, completion August 2021). Award activity has declined notably in recent years, with one award in 2021 following an eight-award cycle in 2014.

Eligible applicants include federally qualified health centers, nonprofit hospitals or clinics, and university health centers providing primary care that maintain a collaborative agreement with a community-based sickle cell disease organization and demonstrate at least five years of experience working with sickle cell disease patients. An active opportunity, HRSA-26-052 (Sickle Cell Disease Regional Care Excellence Program), posted December 11, 2025, solicits Cooperative Agreement applications due July 8, 2026, to establish seven regional coordinating hubs focusing on expanding access and improving quality of care through continuous quality improvement initiatives.

Objective and description

Objective

The objectives of this project is to support the development and establishment of systemic mechanisms to improve the prevention and treatment of sickle cell disease complications, including the coordination of service delivery for individuals with si

Description

The objectives of this project is to support the development and establishment of systemic mechanisms to improve the prevention and treatment of sickle cell disease complications, including the coordination of service delivery for individuals with sickle cell disease; genetic counseling and testing; bundling of technical services related to the prevention and treatment of sickle cell disease; training of health professionals; and identifying and establishing efforts related to the expansion and coordination of education, treatment, and continuity of care for individuals with Sickle Cell Disease as authorized in 42 USC Section 300b-5(b) (Section 1106(b) of the Public Health Service Act).

Eligibility

Applicant eligibility

Eligible entities include, Federally-qualified health center, as defined in section 1905(10(2)(B) of the Social Security Act (42 U.S.C. 1396d(10(2)(B), nonprofit hospital or clinic, or university health center that provides primary health care, that: (1) has a collaborative agreement with a community-based Sickle Cell Disease organization or a nonprofit entity with experience in working with individuals who have Sickle Cell Disease; and (2) demonstrates that either the Federally-qualified health center, the nonprofit hospital or clinic, the university health center, the community-based Sickle Cell Disease organization or the Sickle Cell Disease experts who serve as consultants to the project have at least 5 years of experience in working with individuals who have Sickle Cell Disease.

Beneficiary eligibility

Specialized group (e.g. health professionals, students, veterans), Health Professional, Physically Afflicted (e.g. TB, Arthritis, Heart Disease), Public nonprofit institution/organization Projects will benefit individuals with Sickle Cell Disease and health professionals who provide care for individuals with Sickle Cell Disease.

Uses of assistance

All funds granted should be expended solely for carrying out the approved projects in accordance with Section 712 of the Public Law 103-357.

Use restrictions

All funds granted should be expended solely for carrying out the approved projects in accordance with Section 712 of the Public Law 103-357.

Length and time phasing of assistance

Refer to the notice of funding opportunity (NOFO). Awards are made annually, in accordance with the project period method of awarding grants.

How to apply

Preapplication coordination

An applicant should consult the office or official designated as the single point of contact in his or her State for more information on the process the State requires to be followed in applying for assistance, if the State has selected the program for review.

Criteria for selecting proposals

Evaluation criteria vary based on the grant/cooperative agreement program. Refer to criteria included in the notice of funding opportunity for each specific program.

Award procedure

All qualified applications will be forwarded to an objective review committee. Based on the recommendations of the objective review committee, the HRSA program official with delegated authority is responsible for final selection and funding decisions. Notification is made in writing by a Notice of Award.

Time to approval or disapproval

Final decisions are made 4 to 6 months after receipt of applications.

Renewals

Competitive awards are typically made for up to 2 to 5 years, subject to the availability of funds. After initial awards, annual noncompetitive awards may be made contingent upon the submission of noncompetitive applications/progress reports and availability of funds and a determination that continued funding would be in the best interest of the federal government.

Grant opportunities

Opportunity Status Posted Applications due
​Sickle Cell Disease Regional Care Excellence (SoRCE) Program HRSA-26-052 Closed
Sickle Cell Disease Treatment Demonstration Program HRSA-21-032 Closed
Sickle Cell Disease Treatment Demonstration Regional Collaboratives Program HRSA-17-078 Closed

Grant awards

Latest 10 of 22 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 15 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2025 $14,345,000
FY2024 $13,888,010
FY2023 $24,370,000
FY2022 $12,039,662
FY2021 $4,999,999
FY2020 $4,697,486
FY2019 $3,524,145
FY2018 $3,472,314
FY2017 $3,457,018
FY2016 $3,287,564
FY2015 $3,358,315
FY2014 $3,443,722
FY2013 $3,151,642
FY2012 $3,402,432
FY2011 $3,472,583
FY2010 $3,501,221
FY2009 $2,658,362
FY2008 $200,000
FY2007 $1,278,832
Show all 19

Quick answers

What is Assistance Listing 93.365?

Assistance Listing 93.365 is Sickle Cell Treatment Demonstration Program, a federal grant program run by Health Resources and Services Administration (Department of Health and Human Services).

What is the CFDA number for Sickle Cell Treatment Demonstration Program?

Its CFDA number is 93.365: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.365 awarded?

22 grant awards under 93.365 have obligated $112,548,307 in federal funds to 15 recipients.

Who receives the most funding from 93.365?

The recipients obligated the most under Sickle Cell Treatment Demonstration Program are The Johns Hopkins University ($27,246,836), The Washington University ($19,137,513) and The Center For Comprehensive Care & Diagnosis Of Inherited Blood Disorders ($17,913,819).

How much did 93.365 obligate in fiscal year 2025?

Grants under 93.365 obligated $14,345,000 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.365?

No opportunity listed under 93.365 is open now. The latest, ​Sickle Cell Disease Regional Care Excellence (SoRCE) Program, was posted on December 11, 2025.

On GovTribe

See this program's full record

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