Chronic Diseases: Research, Control, and Prevention

Active

Assistance listing
93.068
Agency
Grant awards
117 $785,135,281 in federal obligations

Program facts

Also known as
Research, Control, and Prevention
Assistance types
  • Cooperative Agreement
  • Block Grant
Treasury account
  • 75-0943-0-1-550
More information

Program details come from SAM.gov Assistance Listings. Updated . Grant award figures come from USAspending.gov.

About this program

The Department of Health and Human Services Centers for Disease Control and Prevention (CDC) funds chronic disease research, control, and prevention initiatives under Assistance Listing 93.068, with the most recent award disbursed on June 28, 2025.

This program supports state and local health agencies, nonprofits, tribal governments, universities, and other organizations implementing evidence-based strategies to prevent and control chronic diseases—particularly diabetes, cardiovascular disease, tobacco-related conditions, and oral health disparities. Awards fund community-based interventions, prediabetes and diabetes prevention programs, tobacco cessation and control initiatives, quitline operations, health systems strengthening, and data-driven approaches addressing social determinants of health. Recipients conduct prevention case management, establish community-clinical linkages, implement policy and environmental changes, and provide training and technical assistance to partner organizations and state programs.

The program awarded 117 grants over nearly two decades, with recent activity showing 26 awards in 2020, declining to 2 awards in 2025, though activity in 2023 and 2024 totaled 24 awards. CDC dominated all funding, obligating $731.9 million across 73 awards; two additional CDC divisions contributed $37.2 million (37 awards) and $16 million (7 awards). The assistance type mix is predominantly Cooperative Agreements (92% of 108 awards) with a smaller Block Grant component (8% of 9 awards). Combined federal and total dollars obligated reached $785.1 million and $787 million respectively, indicating minimal cost-share from recipients.

Representative recent awards include: American Samoa Department of Health ($298,525) strengthening diabetes prevention and management; Puerto Rico Department of Health ($2.5 million) preventing chronic disease and oral health disparities; North American Quitline Consortium ($2.4 million) enhancing tobacco cessation training; and multiple tribal and community-based organizations ($800 thousand to $3.2 million each) implementing culturally adapted chronic disease prevention using a "culture-first approach" in Indian Country and urban Indigenous settings.

No current grant opportunities are open under this Assistance Listing. The most recent posted opportunity was the CDC RFA-DP-25-038 for epilepsy incidence research among children (due January 23, 2025), which addresses a related but distinct chronic disease surveillance mission.

Objective and description

Objective

To assist State and local health agencies, health related organizations, and other public and private organizations in their efforts to prevent and control chronic diseases and disorders through research, development, capacity building, and intervent

Description

Support research to improve detection, diagnosis, treatment, and care of chronic diseases and their complications. To generate new knowledge related to chronic diseases that will improve health and quality of life and eliminate health disparities among segments of the population.

Eligibility

Applicant eligibility

Applications may be submitted by State or local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau). Eligible applicants also include public and private nonprofit organizations, for profit organizations, small, minority, women-owned businesses, universities, colleges, research institutions, hospitals, community-based organizations, faith-based organizations, Federally recognized Indian tribal governments, Indian tribes, and Indian tribal organizations. Foreign institutions may be eligible for some specific programs.

Beneficiary eligibility

The general public will benefit from the objectives of this program.

Uses of assistance

Funds may be used for costs associated with conducting research and surveillance of chronic diseases and their complications. Funds may also be used for program planning and development, to support capacity building, and for evaluation of chronic disease prevention and control programs. CDC will have substantial involvement with the award recipient during performance of the funded activity.

Length and time phasing of assistance

Financial assistance is provided for a 12-month budget period with a period of performance of up to five years subject to the availability of funds and satisfactory progress of the recipient.

How to apply

Criteria for selecting proposals

Applications will be evaluated based on: (1) Agreements between all agencies providing professional and/or supportive care, either voluntarily or for fees; (2) a description of the approach that will be used to provide prevention case management services; and (3) a description of how services will complement/expand existing agency primary and secondary services and specific criteria published in program guidance. Peer review is conducted for all applications.

Award procedure

After review and approval, a Notice of Award (NoA) will be prepared and processed, along with appropriate notification to the public.

Deadlines

Check Grants.gov for any relevant NOFO information regarding processes for applying for assistance.

Time to approval or disapproval

From 3 to 6 months.

Renewals

Project periods are for 1 to 5 years with 12-month budget periods. After initial awards, and subject to availability of funds, projects may be renewed non-competitively contingent upon satisfactory progress by the recipient (as documented in required reports) and the determination that continued funding is in the best interest of the Federal government.

Grant opportunities

Opportunity Status Posted Applications due
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) PA-27-100 Open
Epilepsy Incidence Among Children in the United States RFA-DP-25-038 Closed
Effectiveness of Telehealth-Based Programs to Detect Glaucoma Among High-Risk Populations in Community Health Settings RFA-DP-24-081 Closed
PHS 2022-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) PA-22-177 Closed
PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-22-176 Closed
Assessing the Effectiveness of Programs, Policies, or Practices that Affect Social Determinants of Health to Promote Health Equity and Reduce Health Disparities in Chronic Diseases RFA-DP-23-001 Closed
Assessing the Effectiveness Of Program, Policy, Systems, and Environmental Improvement Strategies that Address SDOH, Promote Health Equity and Reduce Health Disparities In Chronic Diseases RFA-DP-22-004 Past —
PHS 2021-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-21-259 Closed
Improving and Enhancing the US Vision and Eye Health Surveillance System CDC-RFA-DP22-2204 Closed
Real-world effectiveness of structured lifestyle interventions in preventing type 2 diabetes RFA-DP-22-001 Closed
Epidemiology of Lupus: Longitudinal Studies in Population-Based Cohorts RFA-DP-22-002 Closed
PHS 2021-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) PA-21-260 Closed
Reducing Inequities in Cancer Outcomes through Community-Based Interventions on Social Determinants of Health RFA-DP-21-003 Closed
PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) PA-20-261 Closed
PHS 2020-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-20-260 Closed
PHS 2020-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) PA-20-262 Closed
Developing and Disseminating Strategies to Build Sustainable Lupus Awareness, Knowledge, Skills, and Partnerships CDC-RFA-DP20-2008 Closed
PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required PA-19-273 Closed
PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed PA-19-272 Closed
Research to Enhance the US Vision and Eye Health Surveillance System RFA-DP-19-005 Closed
PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-18-574 Closed
PHS 2017-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44]) PA-17-302 Closed
Validation of survey questions to distinguish type 1 and type 2 diabetes among adults with diabetes RFA-DP-17-002 Closed
Community Characteristics Associated with Geographic Disparities in Diabetes and Cardiometabolic Health RFA-DP-17-001 Closed
SBIR/STTR Commercialization Readiness Pilot (CRP) Program: Technical Assistance (SB1) PAR-16-026 Closed
Developing and Disseminating Programs to Build Sustainable Lupus Awareness, Knowledge, Skills and Partnerships CDC-RFA-DP15-1511 Closed
Improving Surveillance and Prevention of Epilepsy Burden in US Communities RFA-DP-15-009 Closed
Evaluation of a Stepped Care Approach for Perinatal Depression Treatment in Obstetrics and GynecologyClinics RFA-DP-15-005 Closed
Comparison and Validation of Screening Tools For Substance Use Among Pregnant Women RFA-DP-15-003 Closed
Epidemiologic Study of Interstitial Cystitis RFA-DP-15-010 Closed
Establish a Vision and Eye Health Surveillance System for the Nation RFA-DP-15-004 Closed
Strengthening Human Resources for Health Capacity in the Republic of Rwanda under the President's Emergency Plan for AIDS Relief (PEPFAR) CDC-RFA-GH15-1568 Closed
Show all 32

Grant awards

Latest 10 of 117 listed here. See the rest on GovTribe.

Top recipients by federal obligations

10 of 94 recipients listed here. See the rest on GovTribe.

Federal obligations by fiscal year

Fiscal year Federal obligations
FY2026 $80,343,482
FY2025 $35,995,949
FY2024 $17,604,517
FY2023 $19,356,565
FY2022 $29,998,983
FY2021 $9,019,433
FY2020 $23,183,470
FY2019 $17,481,166
FY2018 $10,394,308
FY2017 $10,941,524
FY2016 $8,150,888
FY2015 $6,689,428
FY2014 $2,571,661
FY2013 $2,977,839
FY2012 $3,037,218
FY2011 $4,141,692
FY2010 $6,438,784
FY2009 $3,387,464
FY2008 $4,694,251
FY2007 $608,742
Show all 20

Quick answers

What is Assistance Listing 93.068?

Assistance Listing 93.068 is Chronic Diseases: Research, Control, and Prevention, a federal grant program run by Centers for Disease Control and Prevention (Department of Health and Human Services).

What is the CFDA number for Chronic Diseases: Research, Control, and Prevention?

Its CFDA number is 93.068: Assistance Listing numbers were called CFDA numbers before 2018.

How much funding has Assistance Listing 93.068 awarded?

117 grant awards under 93.068 have obligated $785,135,281 in federal funds to 94 recipients.

Who receives the most funding from 93.068?

The recipients obligated the most under Chronic Diseases: Research, Control, and Prevention are Department Of State Health Services ($49,132,704), New Jersey Department Of Health ($47,213,498) and State Of Wisconsin Department Of Health Services ($42,457,530).

How much did 93.068 obligate in fiscal year 2025?

Grants under 93.068 obligated $35,995,949 in federal funds in fiscal year 2025.

Are there open grant opportunities under 93.068?

1 listed opportunity under 93.068 is open or forecasted. The latest, NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional), was posted on June 18, 2025.

On GovTribe

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