Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)

Open Posted

Opportunity number
PAR-25-100
Agency
Applications due
Award size
Not on record

Opportunity facts

Assistance listings
Funding instrument
Grant
Categories
  • Education
  • Health
Eligible applicants
  • Tribal Organizations (Not Federally Recognized)
  • Tribal Governments (Federally Recognized)
  • Small Businesses
  • State Governments
  • Independent School Districts
  • 501(c)(3) Nonprofits
  • Other
  • City/Township Governments
  • Higher Education Inst. (Private)
  • Higher Education Inst. (Public)
  • County Governments
  • Non-501(c)(3) Nonprofits
  • Special District Governments
  • For Profit Organizations
  • Public or Indian Housing Auth.
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institutes of Health is soliciting applications under NOFO PAR-25-100 for pilot and preliminary services research on treating drug, alcohol, and tobacco use disorders through the R34 Clinical Trial Optional mechanism, with applications due October 27, 2027. Eligible applicants include tribal organizations (not federally recognized), federally recognized tribal governments, small businesses, state, county, city/township, and special district governments, independent school districts, 501(c)(3) and non-501(c)(3) nonprofits, public and private higher education institutions, for-profit organizations, and public or Indian housing authorities. The NOFO also lists other eligible applicants: Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving Institutions, HBCUs, TCCUs, federal agencies, faith-based or community-based organizations, regional organizations, non-domestic entities, U.S. territories or possessions, and non-federally recognized tribal governments. The NOFO funds feasibility, acceptability, and utility assessments of novel and commonly used interventions, practices, and policies that optimize access to, and the quality, effectiveness, affordability, and utilization of, substance use disorder treatment and related services, including services for comorbid medical and mental disorders, along with usual trial preparation activities. Program-level guidance recommends a specified project period usually not in excess of 5 years. The federal program description lists four review considerations: scientific and technical merit, feasibility of the research, potential contribution to the national drug abuse problem, and relevance to NIDA priorities. Applicants must follow the General Instructions and the research-specific instructions in application guide PKG00289501, including the "Additional Instructions for Research" section. The opportunity is assigned to CFDA 93.279, Drug Use and Addiction Research Programs, administered by the National Institute on Drug Abuse. The NOFO was posted December 6, 2024.

Synopsis

This Notice of Funding Opportunity (NOFO) encourages pilot and preliminary research in preparation for larger-scale services research effectiveness trials. Relevant trials may test a wide range of approaches, including interventions, practices, and policies designed to optimize access to, and the quality, effectiveness, affordability and utilization of drug, tobacco, or alcohol use disorder treatments and related services, as well as services for comorbid medical and mental disorder conditions. Relevant approaches may include both those that are novel, and those that are commonly used in practice but lack an evidence base. This NOFO provides resources for assessing the feasibility, acceptability, and utility of these approaches, in addition to usual trial preparation activities.

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Files

File Type Posted
PAR-25-100-Full-Announcement.html HTML file
PKG00289501.pdf PDF

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