PAR-25-100-Full-Announcement.html

This Notice of Funding Opportunity (PAR-25-100) from the Department of Health and Human Services National Institutes of Health solicits pilot and preliminary research proposals for larger-scale services research effectiveness trials focused on drug, alcohol, and tobacco use disorders. The grant supports testing of both novel and existing interventions, practices, and policies aimed at optimizing treatment access, quality, effectiveness, affordability, and utilization, including services for comorbid medical and mental health conditions.

The opportunity is available to a wide range of applicants including government entities, higher education institutions, non-profits, for-profits, and tribal organizations. It falls under the Drug Use and Addiction Research Programs (CFDA 93.279) which supports basic and clinical neuroscience, biomedical, behavioral and social science, epidemiologic, health services and health disparity research. The R34 Clinical Trial Optional grant mechanism will fund feasibility studies, acceptability testing, and trial preparation activities, though specific award amounts are not indicated in this file.