Limited Competition: Clinical Research Sites (CRS) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trial Not Allowed)

Closed Posted

Opportunity number
RFA-HL-26-009
Agency
Applications due
Award size
Up to $2,400,000

Opportunity facts

Funding instrument
Cooperative Agreement
Categories
  • Education
  • Health
  • Income Security and Social Services
Eligible applicants
  • Higher Education Inst. (Public)
  • Higher Education Inst. (Private)
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The purpose of this Notice of Funding Opportunity (NOFO) is to renew the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period from 2026-2032. This NOFO, administered by the Department of Health and Human Services National Institutes of Health, is limited to institutions previously funded under RFA-HL-19-008 and will fund up to 13 Clinical Research Sites (CRS) for the MWCCS. The study will utilize a populomics approach to investigate the web of influences impacting the health, quality of life, and survival of adults living with and without HIV. The funding opportunity runs in parallel with two companion U01 NOFOs for a Data Analysis and Sharing Center and a Leadership and Coordination Center.

This NOFO has a posted date of January 16, 2025 and a due date of May 2, 2025. The federal grant programs under which this opportunity is assigned include the NIH Office of Research on Women's Health, Lung Diseases Research, Cardiovascular Diseases Research, and several other relevant medical research initiatives. The awards are expected to be cooperative agreements, with research predominantly conducted at academic and medical research institutions across the United States.

Synopsis

The purpose of this Notice of Funding Opportunity (NOFO) is to renew the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). Continuation of this epidemiological cohort study of middle-aged and older people living with HIV (PLWH), along with comparable people living without HIV (PLWOH) will enable the continued follow-up of a deeply phenotyped cohort of more than 5,600 participants from across the United States. This initiative will utilize a populomics approach, i.e., examination of health determinants across multiple scales of influence (e.g. molecular, cellular, physiological, lifestyle/behavioral, household, neighborhood, environmental, cultural, and sociopolitical) using multi-disciplinary methods to investigate the web of influences impacting the health, quality of life, and survival of adults living with HIV. This NOFO is limited to institutions who were funded under RFA-HL-19-008 and will fund up to 13 Clinical Research Sites (CRS) for the MWCCS. This NOFO runs in parallel with two companion U01 NOFOs: RFA-HL-26-010 (Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)) and RFA-HL-26-011 (Leadership and Coordination Center (LACC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)).

Files

File Type Posted
RFA-HL-26-009-Full-Announcement.html HTML file

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