Expanded Surveillance for Pediatric Infectious Diseases

Forecasted Federal grant Posted

Opportunity number
RFA-IP-27-035
Agency
Applications expected due
Award size
$850,000 to $1,140,000

Opportunity facts

Expected posting
Assistance listings
Funding instrument
Cooperative Agreement
Category
  • Health
Eligible applicants
  • Public or Indian Housing Auth.
  • Non-501(c)(3) Nonprofits
  • Tribal Governments (Federally Recognized)
  • Special District Governments
  • Tribal Organizations (Not Federally Recognized)
  • For Profit Organizations
  • Independent School Districts
  • Higher Education Inst. (Public)
  • City/Township Governments
  • 501(c)(3) Nonprofits
  • State Governments
  • County Governments
  • Higher Education Inst. (Private)
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The Centers for Disease Control and Prevention is soliciting cooperative agreement applications to establish a network of U.S. institutions conducting standardized, prospective, active surveillance of pediatric acute respiratory illness and acute gastroenteritis, with a requirement to apply for Component A (Core Component, supporting inpatient and emergency department surveillance) and optional eligibility to apply for one or more additional components.

Eligible applicants include state governments, county governments, city/township governments, tribal governments (federally recognized), tribal organizations (not federally recognized), special district governments, public or Indian housing authorities, independent school districts, higher education institutions (public and private), 501(c)(3) nonprofits, non-501(c)(3) nonprofits, and for-profit organizations.

The network will follow CDC-established standardized protocols to enroll patients meeting standard symptom criteria, confirm viral infections using approved molecular assays, and generate robust estimates of effectiveness for influenza, rotavirus, respiratory syncytial virus, and other prevention products against respiratory and enteric viral illness in pediatric populations. Recipients will identify acute gastroenteritis and acute respiratory illness among inpatient and emergency department patients; outpatient surveillance through urgent care centers represents an optional activity. Additional optional components allow applicants to study immune response and infection, and to study immune response and immunization.

Findings will improve diagnosis and treatment protocols, inform prevention product recommendations, guide public health strategies, and reduce viral illness-associated hospitalizations and healthcare utilization among children.

This opportunity falls under CFDA 93.083 (Prevention of Disease, Disability, and Death through Immunization and Control of Respiratory and Related Diseases). Cooperative agreement periods of performance range from 1 to 5 years, with initial budget periods typically spanning 12 months and opportunity for non-competitive continuation contingent on satisfactory progress and Federal government determination of continued funding merit. Applications will be evaluated on scientific and technical merit, funds availability, and relevance to program and CDC priorities.

Forecast synopsis

The purpose of this Notice of Funding Opportunity (NOFO) is to support a network of U.S. institutions that will conduct standardized, prospective, active surveillance of pediatric acute respiratory illness (ARI) and acute gastroenteritis (AGE). The network will focus on respiratory and enteric viruses among pediatric patients seeking healthcare.

In addition, the network will generate robust estimates of the effectiveness of influenza, rotavirus, respiratory syncytial virus (RSV) and other prevention products against respiratory and enteric viral illnesses in this population.

Recipients will identify AGE and ARI illnesses among patients seeking healthcare or diagnostic testing for acute illness among inpatient and emergency department populations. Recipients may also include patients seeking care in outpatient clinics, such as urgent care centers, as an optional activity.

This is a multi-component NOFO. You must apply for ComponentA (Core Component). You may also apply for one or more optional components.

Component A - Core Component (Required)

  • Support inpatient and emergency department pediatric surveillance
  • Follow the standardized protocol established by CDC

Optional Components

  • Component B: Support outpatient pediatric surveillance
  • Component C: Study immune response and infection
  • Component D: Study immune response and immunization

Recipients will enroll patients meeting standard symptom criteria and confirm viral infections using approved molecular assays. The network will use the data to estimate prevention product effectiveness, hospitalization rates, and information on the natural history of medically attended diseases.

Findings of this NOFO will:

  • Improve best practices for diagnosis and treatment protocols
  • Inform prevention product recommendations
  • Guide public health strategies
  • Reduce viral illness-associated hospitalizations and healthcare utilization among children

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