Enabling Discovery through GEnomics

Closed Posted

Opportunity number
21-546
Agency
Applications due
Award size
Up to $2,000,000

Opportunity facts

Assistance listings
Funding instrument
Grant
Category
  • Science and Technology and other Research and Development
Eligible applicants
  • Other
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Science Foundation (NSF) and the National Institutes of Health (NIH) are jointly offering the Enabling Discovery through GEnomics (EDGE) program to support research aimed at advancing the understanding of comparative and functional genomics. The program seeks the development of innovative tools, technologies, resources, and infrastructure that will advance biological research focused on identifying the causal mechanisms connecting genes and phenotypes. Additionally, the program supports functional genomic research that addresses the mechanistic basis of complex traits in diverse organisms within the context in which they function. The evaluation criteria will focus on the potential of the proposed research to uncover the rules underlying genomes-to-phenomes relationships and predict phenotype, as well as its alignment with the priorities of the NSF and NIH. The deadline for submitting proposals is February 20, 2025.

The EDGE program offers funding opportunities with a typical range of $200,000 to over $1 million per award, and project durations generally spanning 2-5 years. The proposed work is expected to be conducted primarily at the facilities of the recipient organizations, which can include universities, non-profit organizations, and small businesses across the United States, with some opportunities for international collaboration.

Synopsis

Through the Enabling Discovery through GEnomics (EDGE) program, the National Science Foundation (NSF) and the National Institutes for Health (NIH) support research to advance understanding of comparative and functional genomics. The EDGE program supports the development of innovative tools, technologies, resources, and infrastructure that advance biological research focused on the identification of the causal mechanisms connecting genes and phenotypes. The EDGE program also supports functional genomic research that addresses the mechanistic basis of complex traits in diverse organisms within the context (environmental, developmental, social, and/or genomic) in which they function. These goals are essential to uncovering the rules that underlie genomes-to-phenomes relationships and predict phenotype, an area relevant to Understanding the Rules of Life: Predicting Phenotype, one of the 10 Big Ideas for NSF investment. The goals also support the NHGRI priority to establish the roles and relationships of all genes and regulatory elements in pathways, networks, and phenotypes.

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