Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trial Not Allowed)
Closed Posted
- Opportunity number
- PAR-25-214
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Up to $200,000
Opportunity facts
- Assistance listings
-
- 93.173 Research Related to Deafness and Communication Disorders
- 93.233 National Center on Sleep Disorders Research
- 93.351 Research Infrastructure Programs
- 93.837 Cardiovascular Diseases Research
- 93.838 Lung Diseases Research
- 93.839 Blood Diseases and Resources Research
- 93.840 Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
- 93.855 Allergy and Infectious Diseases Research
- 93.865 Child Health and Human Development Extramural Research
- 93.866 Aging Research
- Funding instrument
- Grant
- Categories
-
- Health
- Income Security and Social Services
- Eligible applicants
-
- Independent School Districts
- Other
- Non-501(c)(3) Nonprofits
- Public or Indian Housing Auth.
- For Profit Organizations
- Tribal Organizations (Not Federally Recognized)
- Small Businesses
- 501(c)(3) Nonprofits
- State Governments
- Special District Governments
- Higher Education Inst. (Private)
- County Governments
- Higher Education Inst. (Public)
- City/Township Governments
- Tribal Governments (Federally Recognized)
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The Department of Health and Human Services National Institutes of Health (NIH) is seeking grant applications for the Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trial Not Allowed). The funding opportunity is part of the INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project and aims to support exploratory and innovative research to develop, characterize, or improve animal models and related biological materials for Down syndrome research. Key focus areas include various animal models, genetic resources, single cell/subcellular atlases, advanced informatics technologies (AI/ML), and integration of multiple animal models. Eligible applicants include a wide range of organizations such as higher education institutions, tribal governments, nonprofits, small businesses, and government entities. The opportunity is posted with a due date of January 7, 2026.
Recent federal grant awards under related programs have ranged from smaller exploratory grants around $100,000 to larger multi-year projects exceeding $14 million. The research activities are expected to be conducted at the facilities of the recipient organizations across the United States.
Synopsis
The INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project encourages exploratory and innovative research to develop, characterize, or improve animal models and related biological materials for Down syndrome (DS) related research and to improve access to information about or from the use of animal models for DS research. The animal models and related biological materials developed must have utility in targeted or basic science studies in areas highly relevant to DS. With this funding opportunity announcement, the INCLUDE Project encourages, but is not limited to, projects focusing on development of various animal models, genetic resources, atlases at a single cell or subcellular level, advanced informatics technologies including artificial intelligence (AI) or machine learning (ML), and integration of multiple animal models and technology platforms for enhancing rigor and reproducibility of preclinical DS research.
Files
| File | Type | Posted |
|---|---|---|
| PAR-25-214-Full-Announcement.html | HTML file |
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