PAR-25-214-Full-Announcement.html

This file contains details for a Notice of Funding Opportunity (NOFO) PAR-25-214, titled "Development of Animal Models and Related Biological Materials for Down Syndrome Research (R21 Clinical Trial Not Allowed)." The grant opportunity is part of the INCLUDE Project (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) administered by the Department of Health and Human Services National Institutes of Health.

The funding opportunity supports research to develop and improve animal models and biological materials for Down syndrome research, with specific focus on targeted and basic science studies. Key research areas include development of various animal models, genetic resources, single cell/subcellular atlases, advanced informatics technologies (AI/ML), and integration of multiple animal models. The grant is available to a wide range of applicants including higher education institutions, tribal governments, nonprofits, small businesses, and government entities. The opportunity falls under multiple CFDA programs including Lung Diseases Research (93.838), Cardiovascular Diseases Research (93.837), Child Health and Human Development (93.865), and Aging Research (93.866), among others.