Ultra-Performance Liquid Chromatograph-Tandem Mass Spectrometer System (UPLC-MS/MS) in tandem with a triple quadrupole mass spectrometry system

The U.S. Food and Drug Administration's National Center for Toxicological Research is procuring one Ultra-Performance Liquid Chromatograph-Tandem Mass Spectrometer System (UPLC-MS/MS) with a triple quadrupole mass spectrometry system, along with a 12-month post-warranty preventive maintenance and repair service agreement. The equipment will be used for critical research applications including assessing dermal penetration of polyfluoroalkyl substance (PFAS) contaminants, characterizing tattoo pigment absorption, and conducting pharmacokinetic measurements on nitrosamine drug substance-related impurities. The procurement is structured as a Request for Quote (RFQ) under a firm-fixed price contract with full and open competition, though it targets small businesses. The government requires newly manufactured equipment that meets comprehensive technical specifications for both the mass spectrometer and liquid chromatograph components. Offers are due by August 5, 2025, at 1:00 PM Central Time, providing vendors with a very tight seven-day response window from the July 29, 2025 posting date.

This procurement does not utilize any set-aside designations, making it available to all qualified contractors despite targeting small businesses. The solicitation does not identify any incumbent contractors or potential award values, focusing instead on technical requirements and delivery specifications. The successful contractor must deliver, install, provide onsite qualification, and conduct training within 120 calendar days from the contract award date. The equipment and services will be performed in Jefferson, Arkansas 72079, at the FDA's National Center for Toxicological Research facility. The procurement falls under NAICS code 334516 for Analytical Laboratory Instrument Manufacturing and PSC code 6640 for Laboratory Equipment and Supplies, indicating the specialized nature of the scientific instrumentation being acquired.