Sources Sought – RRBS Sequencing Services

Closed Pre-Solicitation Posted

Solicitation number
36C241-26-AP-4037
Agency
Responses due
Set-aside
Service-Disabled Veteran-Owned Small Business

Opportunity facts

Place of performance
Bedford, Massachusetts 01731, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The Department of Veterans Affairs, on behalf of the VA Bedford Healthcare System, is conducting a sources-sought notice to identify Service-Disabled Veteran-Owned Small Businesses (SDVOSBs) and Veteran-Owned Small Businesses (VOSBs) capable of providing Reduced Representation Bisulfite Sequencing (RRBS) services, with capability statements due August 12, 2026 at 11:00 AM EST. This procurement is set-aside for SDVOSBs and VOSBs under the Veterans First Contracting Program and issued to determine appropriateness under the VA "Rule of Two."

The work involves DNA methylation profiling of approximately 269 de-identified human post-mortem choroid plexus tissue samples supporting a neurodegenerative disease research program. Required services include sample handling and quality control, bisulfite conversion, library preparation, Illumina paired-end sequencing at approximately 30 million read pairs per sample, and raw data alignment, methylation calling, and genome browser track generation. The anticipated turnaround is 6–8 weeks.

Interested firms must submit capability statements addressing technical capability, business size and status, and facility location to Chelsea Cortright at Chelsea.Cortright@va.gov, referencing ID# 36C241-26-AP-4037 in the subject line. This sources-sought notice is issued for market research purposes under FAR Part 10 and VAAR Parts 810 and 819; no contract will result directly from this notice.

Notice text

This is a Sources Sought Notice for market research purposes only and does not constitute a solicitation. The Department of Veterans Affairs, on behalf of the VA Bedford Healthcare System, is seeking to identify qualified Service-Disabled Veteran-Owned Small Businesses (SDVOSBs) and Veteran-Owned Small Businesses (VOSBs) capable of providing Reduced Representation Bisulfite Sequencing (RRBS) services for DNA methylation profiling of approximately 269 de-identified human post-mortem choroid plexus tissue samples in support of a neurodegenerative disease research program.

Services required include sample handling and QC, bisulfite conversion, library preparation, Illumina paired-end sequencing (~30 million read pairs/sample), and raw data alignment, methylation calling, and genome browser track generation, with an anticipated 6–8 week turnaround. This notice is issued under FAR Part 10, VAAR Part 810, and VAAR Part 819 in accordance with the Veterans First Contracting Program (38 U.S.C. 8127–8128) to determine whether a set-aside is appropriate under the VA "Rule of Two." Interested firms must submit a capability statement addressing technical capability, business size/status, and facility location no later than 11:00 AM EST on August 12, 2026, to Chelsea Cortright at Chelsea.Cortright@va.gov, referencing ID# 36C241-26-AP-4037 in the subject line. This is not a request for proposals, and no contract will result directly from this notice.

Files

File Type Posted
Sources_Sought_Notice_RRBS_36C241-26-AP-4037.docx DOCX document

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