Sources sought RNA sequencing

Closed Pre-Solicitation Posted

Solicitation number
140G0326Q0220
Agency
Responses due
Set-aside
Total Small Business

Opportunity facts

Points of contact

Notice details come from SAM.gov. Updated .

About this opportunity

The U.S. Geological Survey is conducting market research to identify qualified vendors capable of RNA sequencing services on an Illumina NovaSeq X Plus platform, with capability statements due September 15, 2026 at 0700 Pacific Time. This sources sought is classified as a Total Small Business set-aside.

The work involves polyA-selected RNA library preparation and high-throughput sequencing for ninety-six RNA samples using the Watchmaker Genomics mRNA kit or equivalent, quality control assessments including TapeStation analysis, and 175 bp single-read sequencing across two lanes. Vendors must guarantee a minimum yield of 10 million pass-filter reads per sample with approximately 800 million pass-filter reads per lane. All work must be completed within 45 calendar days of sample receipt. Data delivery requires encrypted transfer methods (SFTP, HTTPS, or secure portal) with no third-party data sharing permitted.

Capability statements should detail per-sample pricing for library preparation and per-lane pricing for sequencing, with optional services clearly itemized. Vendors must identify their small business or large business status under the 541380 NAICS code (size standard $19.0 million). Responses must be submitted electronically to Anthony_berry@ios.doi.gov. This announcement is for acquisition planning purposes only and does not commit the Government to award a purchase order or contract. The Government will not reimburse response costs.

Notice text

Sources Sought

The U.S. Geological Survey (USGS) is conducting market research to determine the availability of qualified businesses capable of RNA sequencing on an ilumina NovaSeq X Plus and library preparation described in the attached statement of work. This sources sought announcement is not a request for quote or proposal and the Government is not committed to award of a purchase order or contract pursuant to this announcement. The information resulting from this market research is simply for planning purposes to assist the Government in determining its acquisition strategy. The Government will not pay for any costs incurred in the preparation of information for responding to this notice.

NAICS code: 541380 – Testing Laboratories and Services
Size Standard $19.0 million

All responsible sources may submit capability statements detailing the ability of their service to meet the statement of work included with this announcement.
Please indicate whether you are a small business or large business under this size standard in your response.

Responses to this announcement shall only be accepted through electronic mail addressed to Anthony_berry@ios.doi.gov and must be uploaded and received in their entirety no later than September 15th at 0700 Pacific time.

EXAMPLE statement of work attached subject to change.

Files

File Type Posted
Sources_Sought_1.docx DOCX document

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