Notice of Intent to issue a Sole Source Award to generate and optimize high-affinity nucleic acid aptamers capable of semi-quantitative detection of TFV-DP and/or TFV for use in both plate-based assays and POC platforms.
Closed Pre-Solicitation Posted
- Solicitation number
- 75D30126R73457
- Agency
-
CDC Office of Acquisition Services
Centers for Disease Control and Prevention, Department of Health and Human Services
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- PSC
- AJ12 General Science And Technology R&D Services; General Science And Technology; Applied Research
- Place of performance
- Chapel Hill, North Carolina 27599, United States
- Points of contact
Notice details come from SAM.gov. Updated .
About this opportunity
The Centers for Disease Control and Prevention Division of HIV Prevention intends to award a sole-source firm-fixed-price purchase order to the University of North Carolina at Chapel Hill, Department of Chemistry, by June 2, 2026, for generation and optimization of high-affinity nucleic acid aptamers capable of semi-quantitative detection of TFV-DP and/or TFV for use in plate-based assays and point-of-care platforms.
UNC was identified as uniquely qualified due to its role as co-inventor of the FTC aptamer previously developed for antiretroviral-detection research and its established methodologies compatible with CDC's current assay development efforts. The agency states UNC is the only source reasonably available capable of performing the required work within the required timeframe and technical specifications. Switching to another vendor's aptamer would require restart of the entire optimization process and would be incompatible with the already-developed, existing aptamer detecting emtricitabine.
This notice of intent is not a request for competitive quotations; however, all quotations or responses received within 15 days of issuance shall be considered by the government. The government reserves discretion to determine whether to complete the proposed contract based on responses received. Quotations should be emailed to the contract specialist at zvm0@cdc.gov by June 2, 2026. The procurement is classified under NAICS 541715 (Medical Research and Development Laboratories or Services) and PSC AJ12 (General Science and Technology R&D Services).
Notice text
The Centers for Disease Control and Prevention Division of HIV Prevention (DHP)/Laboratory Branch intends to award a sole source Firm-fixed-price purchase order to the University of North Carolina at Chapel Hill, Department of Chemistry to generate and optimize high-affinity nucleic acid aptamers capable of semi-quantitative detection of TFV-DP and/or TFV for use in both plate-based assays and POC platforms. This contract action is for commercial services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 12.102-1. NAICS 541715 - Medical Research and Development Laboratories or Services (except Biotechnology and Nanotechnology Research and Development). UNC was identified as uniquely qualified due to its role as a co-inventor of the FTC aptamer previously developed for ARV detection research, and established methodologies compatible with CDC’s current assay development efforts. UNC is the only source reasonably available capable of performing the required work within the required timeframe and technical specifications. Changing to another vendor’s aptamer would severely impact the CDC’s progress in this area, requiring a start over of the entire process of optimization and would not be compatible with the already developed, existing aptamer detecting emtricitabine. This notice of intent is not a request for competitive quotations; however, all Quotations/ responses received within 15 days of the issuance of this notice shall be considered by the government. A determination by the government not to complete this proposed contract based upon responses to this notice is solely within the discretion of the government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. Any quotation/response should be emailed to the contract specialist at email zvm0@cdc.gov by 06/02/2026.
Similar open opportunities
| Opportunity | Agency | Set-aside | Responses due |
|---|---|---|---|
| CDC Typefi Orion Cloud Teams Software Licenses and Implementation | — | No set-aside | |
| Notice of Intent to Sole Source a Thermo Orbitrap Fusion Lumos and Thermo RSLCnano UPLC Maintenance Agreement | CDC Office of Acquisition Services | No set-aside |
On GovTribe
Work this opportunity
- Track it in your pipeline
- Find teaming partners
- Similar opportunities
- Ask GovTribe AI about this opportunity