NIEHS - Single Cell Sequencing and Spatial Transcriptomics

The National Institute of Environmental Health Sciences (NIEHS), a component of the Department of Health and Human Services, intends to negotiate a sole-source procurement with 10X Genomics, Inc. for a specialized Chromium X and CytAssist system used in single cell sequencing and spatial transcriptomics research. The procurement is specifically targeting the acquisition of advanced genomic equipment capable of performing single cell gene expression experiments on patient blood and bone marrow samples. NIEHS will utilize FAR Part 13 Simplified Acquisition Procedures to execute this contract, with a focus on 10X Genomics as the only responsible source due to the highly specialized nature of their instrument. Potential alternative vendors may submit a capability statement to Carlton Taylor by March 31, 2024 at 12:00 PM EST, though the government retains complete discretion over the procurement process. The solicitation suggests that using an alternative instrument would require extensive and costly revalidation of existing testing procedures.

The contract opportunity is not set aside for any specific business category and will be performed at the NIEHS location in Research Triangle Park, NC. The period of performance is scheduled from March 31, 2025 to March 30, 2026, spanning approximately one year. 10X Genomics' manufacturing operations are regulated by Current Good Manufacturing Practices (cGMPs) as mandated by the Food and Drug Administration, which adds credibility to their selection. The procurement includes multiple gene expression chip kits, sample preparation kits, and an associated service agreement. While specific award values are not explicitly stated, the contract falls under the Simplified Acquisition Threshold and involves highly specialized analytical laboratory instrumentation classified under NAICS category 334516 (Analytical Laboratory Instrument Manufacturing) and PSC category 6640 (Laboratory Equipment and Supplies).