NGS services to support clinical research

The National Institutes of Health, Office of Logistics and Acquisition Operations, seeks Next Generation Sequencing services to support clinical and research activities related to bone marrow failure syndromes, with quotations due May 29. The procurement is set aside for small business, issued as a combined synopsis/solicitation for commercial items under FAR 12.603, not expected to exceed the simplified acquisition threshold.

Place of performance is the NIH Office of the Director in Bethesda, Maryland. The contract runs from June 1, 2026 through May 31, 2027. The Government anticipates approximately 144 total samples throughout the period, shipped in multiple batches with no guaranteed batch quantities or shipment frequency.

The contractor must maintain current CLIA certification and propose sequencing panels and methodologies capable of covering clinically relevant genes associated with hematologic malignancies and bone marrow failure syndromes, including but not limited to UBA1, TERT, GATA2, CALR, FLT3, and NPM1. A mandatory 10-calendar-day turnaround time applies from specimen receipt through final analysis and reporting. Single Primer Extension chemistry is referenced, though alternative methodologies such as hybrid capture may be considered acceptable only if they do not materially alter comparability, consistency, or continuity of longitudinal sequencing data. The contractor must provide capability for automated extraction of both DNA and RNA from various tissue types, supply specimen shipment materials, and maintain secure electronic reporting with appropriate safeguards for patient-sensitive information accessible only through authenticated access methods.

The NAICS code is 621511, Medical Laboratories, with a small business size standard of $41.5 million. PSC code is Q301, Reference Laboratory Testing. The award will be firm-fixed-price to the responsible offeror representing best value. Quotations should be submitted to Nicholas Capobianco. Applicable FAR clauses include 52.204-13, 52.204-18, 52.212-4, 52.212-5, and 52.217-8, along with HHSAR 352.222-70.