Methylation Sequencing Library Preparation Kits fo

The National Heart, Lung, and Blood Institute intends to procure methylation sequencing library preparation kits via sole-source award from Integrated DNA Technologies by September 30, 2026, with responses due September 14, 2026. The acquisition is non-competitive under FAR Part 13 Simplified Acquisition Procedures.

The procurement supports epigenetic profiling research on cell-free DNA in organ transplant recipients within the Division of Intramural Research. Work is performed at NHLBI.

The kits are mandatory for maintaining data consistency and comparability across an established study cohort; the laboratory has validated the IDT kits using clinical samples from organ transplant patients and determined that continued use is essential. The IDT products are optimally designed to minimize adapter and primer dimer formation challenges inherent in cell-free DNA library preparation, a requirement that market research and technical evaluation confirmed is met uniquely by these kits.

The specific items required are 12 kits of xGen Methyl-Seq Library Prep (Catalog No. 10009824), 6 kits of xGen 2S Plus DNA Library Prep (Catalog No. 10009878), and 1 kit of xGen UDI 10nt Primer Plates 1-16 (Catalog No. 10008054). Estimated total cost is $77,117.11 including shipping and handling.

Interested vendors must submit unit pricing, list pricing, shipping costs, delivery period, payment terms, F.O.B. point, UEI, TIN, and business size certification. All respondents must maintain active SAM registration. Responses should be directed to Contract Specialist Rashida Ferebee at Rashida.Ferebee@nih.gov.