Metabolomic Analysis Services for NIDDK

The National Institutes of Health, specifically the National Institute of Child Health and Development (NICHD) supporting the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), intends to award a sole-source contract for Metabolomic Analysis Services. The procurement is being issued as a pre-solicitation non-competitive notice of intent to award to Metabolon, Inc., which will support the Liver Diseases Branch's research on microbiomes and their effects on host physiology and immune responses. The contractor will be required to analyze biological samples using ultra-high performance liquid chromatography/tandem mass spectrometry to identify metabolites, provide statistical analysis, and deliver results through a client portal. The contract falls under NAICS code 541380 (Testing Laboratories and Services) and PSC code Q301 (Reference Laboratory Testing). Interested parties may submit capability statements electronically by 12:00 PM Eastern Daylight Time on September 17, 2025, and must maintain active System for Award Management (SAM) registration.

This opportunity does not utilize any set-aside designations and is structured as a sole-source award to the incumbent contractor, Metabolon, Inc. The specific scope involves analyzing 24 brown and 24 white adipose tissue samples plus 24 plasma samples from two distinct mouse groups with different microbiota and weight gain characteristics, totaling 72 samples for analysis. The contract establishes a 5-month period of performance from the award date, with results required within 16 weeks of the contractor receiving the biological samples. While the pre-solicitation notice does not specify the contract value or budget range, the specialized nature of the metabolomic analysis services and the specific sample quantities indicate a targeted research initiative requiring highly specialized laboratory capabilities. The timeline suggests an expedited research schedule with relatively quick turnaround requirements for the analytical results.