Effect of Radiation Quality and Galactic Cosmic Radiation Simulation on the Risk of Carcinogenesis in an Outbred Mouse Model (HS/Npt)
Closed Solicitation Posted
This opportunity was awarded. See the award notice from .
- Solicitation number
- 80JSC026Q0003
- Agency
-
Johnson Space Center
National Aeronautics and Space Administration
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Place of performance
- Houston, Texas, United States
- Points of contact
Notice details come from SAM.gov. Updated .
About this opportunity
NASA Johnson Space Center is soliciting offers for research services to study the effects of radiation quality and galactic cosmic radiation simulation on carcinogenesis risk in outbred HS/Npt mice. The primary objectives are to determine how radiation quality, dose, and dose rate affect cancer initiation, promotion, and progression in this mouse model and to establish relative biological effectiveness (RBE) and quality factor estimates for space-relevant radiation exposures. Key contract requirements include designing and executing experiments utilizing 3,500 outbred mice (1,750 per year for two years), conducting exposures at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory, biobanking specified tissues with comprehensive metadata, and delivering annual interim progress reports and a final report. Evaluation of proposals will employ a two-step process: Step One screens for mandatory requirements (confirmation of study focus and facility capacity for 2,000 rodents), while Step Two applies a trade-off evaluation emphasizing Technical Acceptability and Past Performance significantly more than Price. The proposal deadline is March 13, 2026 at 1:00 PM CST, with offers submitted to Joshua.r.hlavenka@nasa.gov and Katelyn.r.jaime@nasa.gov; all amendments and questions/answers were finalized by March 2, 2026.
This is an unrestricted acquisition with no set-aside designation, open to all responsible sources regardless of NAICS code or company size. No current incumbent or contractor name is referenced in the solicitation materials. The contract is structured as a firm fixed price award with a base period covering cancer testing research and three optional work packages for Central Nervous System studies, Cardiovascular Disease studies, and Sex Differences studies, along with a six-month service extension option. The performance period extends from April 1, 2026 through March 29, 2030 (approximately four years), with NASA providing animal breeding, shipping to NSRL, and beam time at no cost while contractors must budget for animal housing, travel to the NSRL facility in Upton, New York, experimental execution, and tissue sample processing. Work will be performed at the contractor's home institution for post-radiation animal housing and tissue evaluations, with some activities potentially conducted at Brookhaven National Laboratory in Upton, New York.
Notice text
2 versions
Update #2 · Latest ·
This notice is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; offers are being requested and a written solicitation will not be issued.
This notice is being issued as a Request for Quote (RFQ) under solicitation number 80JSC026Q0003 for the study of the Effect of Radiation Quality and Galactic Cosmic Radiation on Risks of Carcinogenesis in Outbred Mice contract.
The provisions and clauses in the RFP are those in effect through FAC 2025-06.
The NAICS Code and Size Standard are 541715 and 1000 employees, respectively. The offeror shall state in their offer their size status for this acquisition.
All responsible sources may submit an offer which shall be considered by the agency.
Offers for the items(s) described above are due by 1:00 PM CST on 03/13/2026 to Joshua.r.hlavenka@nasa.gov and Katelyn.r.jaime@nasa.gov and must include, solicitation number, FOB destination to this Center, proposed delivery schedule, discount/payment terms, warranty duration (if applicable), taxpayer identification number (TIN), identification of any special commercial terms, and be signed by an authorized company representative. Offerors are encouraged to use the Standard Form 1449, Solicitation/Contract/Order for Commercial Items form found at URL:https://www.gsa.gov/forms-library/solicitationcontractorder-commercial-items
The following clauses and provisions are incorporated; full text of the clauses and provisions may be accessed electronically at:
FAR - https://www.acquisition.gov/browse/index/far
NFS - https://www.hq.nasa.gov/office/procurement/regs/NFS.pdf
Offerors shall provide the information required by FAR 52.212-1, Instructions to Offerors-Commercial Items, (SEP 2023) which is incorporated by reference.
If the end product(s) offered is other than domestic end product(s) as defined in the clause entitled "Buy American Act -- Supplies," the offeror shall so state and shall list the country of origin.
FAR 52.212-2, Evaluation -- Commercial Items, (NOV 2021) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors are in descending order of importance and shall be used to evaluate offers:
- Technical Acceptablility
- Past Performance
- Price
Technical Acceptability and Past Performance, when combined, are significantly more important than Price. Price is not the most important evaluation factor, but its degree of importance will increase commensurably with the degree of equality among different Quoter’s Technical and Past Performance quotes.
All offerors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications -- Commercial Items (OCT 2025) or complete electronic annual representations and certifications at SAM.gov with its offer.
FAR 52.212-4, Contract Terms and Conditions-Commercial Items, (Nov 2023) is applicable.
FAR 52.212-5, Contract Terms and Conditions Required To Implement Statutes or Executive Orders-Commercial Items, (Nov 2023) is applicable and the following identified clauses are incorporated by reference: Please see attached solicitation.
NASA Clause 1852.215-84, Ombudsman, is applicable. The Center Ombudsman for this acquisition can be found at : https://www.hq.nasa.gov/office/procurement/regs/Procurement-Ombuds-Comp-Advocate-Listing.pdf
This posting, in addition to any attached documents, will be available on www.Sam.gov. Potential offerors will be responsible for downloading their own copy of this combination synopsis/solicitation and amendments (if any).
Prospective offerors are encouraged to notify this office of their intent to submit an offer. All contractual and technical questions must be submitted electronically via email to Johsua Hlavenka at joshua.r.hlavenka@nasa.gov and Katelyn Jaime at katelyn.r.jaime@nasa.gov not later than 02/27/2026 at 1:00 PM CST. Telephone questions will not be accepted.
Responses to this combined synopsis/solicitation must be received via email at joshua.r.hlavenka@nasa.gov no later than 1:00 PM CST on 03/13/2026.
The Government is not responsible for any failure attributable to the transmission or receipt of documents submitted using electronic means, including the missing of any established deadlines.
Failure to submit a complete electronic proposal by the due date and time specified for this RFP shall result in the proposal being considered late, and shall be handled in accordance with FAR 52.212-1(f).
Update #1 ·
This notice is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; offers are being requested and a written solicitation will not be issued.
This notice is being issued as a Request for Proposal (RFP) under solicitation number 80JSC026R0010 for the study of the Effect of Radiation Quality and Galactic Cosmic Radiation on Risks of Carcinogenesis in Outbred Mice contract.
The provisions and clauses in the RFP are those in effect through FAC 2025-06.
The NAICS Code and Size Standard are 541715 and 1000 employees, respectively. The offeror shall state in their offer their size status for this acquisition.
All responsible sources may submit an offer which shall be considered by the agency.
Offers for the items(s) described above are due by 1:00 PM CST on 03/13/2026 to Joshua.r.hlavenka@nasa.gov and Katelyn.r.jaime@nasa.gov and must include, solicitation number, FOB destination to this Center, proposed delivery schedule, discount/payment terms, warranty duration (if applicable), taxpayer identification number (TIN), identification of any special commercial terms, and be signed by an authorized company representative. Offerors are encouraged to use the Standard Form 1449, Solicitation/Contract/Order for Commercial Items form found at URL:https://www.gsa.gov/forms-library/solicitationcontractorder-commercial-items
The following clauses and provisions are incorporated; full text of the clauses and provisions may be accessed electronically at:
FAR - https://www.acquisition.gov/browse/index/far
NFS - https://www.hq.nasa.gov/office/procurement/regs/NFS.pdf
Offerors shall provide the information required by FAR 52.212-1, Instructions to Offerors-Commercial Items, (SEP 2023) which is incorporated by reference.
If the end product(s) offered is other than domestic end product(s) as defined in the clause entitled "Buy American Act -- Supplies," the offeror shall so state and shall list the country of origin.
FAR 52.212-2, Evaluation -- Commercial Items, (NOV 2021) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors are in descending order of importance and shall be used to evaluate offers:
- Technical Acceptablility
- Past Performance
- Price
Technical Acceptability and Past Performance, when combined, are significantly more important than Price. Price is not the most important evaluation factor, but its degree of importance will increase commensurably with the degree of equality among different Quoter’s Technical and Past Performance quotes.
All offerors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications -- Commercial Items (OCT 2025) or complete electronic annual representations and certifications at SAM.gov with its offer.
FAR 52.212-4, Contract Terms and Conditions-Commercial Items, (Nov 2023) is applicable.
FAR 52.212-5, Contract Terms and Conditions Required To Implement Statutes or Executive Orders-Commercial Items, (Nov 2023) is applicable and the following identified clauses are incorporated by reference: Please see attached solicitation.
NASA Clause 1852.215-84, Ombudsman, is applicable. The Center Ombudsman for this acquisition can be found at : https://www.hq.nasa.gov/office/procurement/regs/Procurement-Ombuds-Comp-Advocate-Listing.pdf
This posting, in addition to any attached documents, will be available on www.Sam.gov. Potential offerors will be responsible for downloading their own copy of this combination synopsis/solicitation and amendments (if any).
Prospective offerors are encouraged to notify this office of their intent to submit an offer. All contractual and technical questions must be submitted electronically via email to Johsua Hlavenka at joshua.r.hlavenka@nasa.gov and Katelyn Jaime at katelyn.r.jaime@nasa.gov not later than 02/27/2026 at 1:00 PM CST. Telephone questions will not be accepted.
Responses to this combined synopsis/solicitation must be received via email at joshua.r.hlavenka@nasa.gov no later than 1:00 PM CST on 03/13/2026.
The Government is not responsible for any failure attributable to the transmission or receipt of documents submitted using electronic means, including the missing of any established deadlines.
Failure to submit a complete electronic proposal by the due date and time specified for this RFP shall result in the proposal being considered late, and shall be handled in accordance with FAR 52.212-1(f).
Files
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Notice history
| Notice | Type | Posted |
|---|---|---|
| Mouse Irradiation & Cosmic Carcinogenesis Investigation - MICCI | Award Notice | |
| This notice | Solicitation | |
| Effect of Radiation Quality and Galactic Cosmic Radiation Simulation on the Risk of Carcinogenesis in an Outbred Mouse Model (HS/Npt) | Pre-Solicitation |
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