Cell Line Expressing Human Voltage-gated Sodium Channels

Solicitation extended through 16 September 2022.

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in accordance with FAR Part 12 - Acquisition of Commercial Items Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The combined synopsis/solicitation number is W91ZLK-22-Q-0062 for Proposal. This solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2022-07 (August 10, 2022).

The Government contemplates award of a Firm-Fixed Price Contract for the purchase of Cell Line Expressing Human Voltage-gated Sodium Channels.  This is a solution to measure the effects of synthesized conotoxins on its respective target. Cell line should be rigorously and continuously validated for accurate pharmacology with screening and profiling services used to screen millions of compounds. There should be flexibility in the cell line backgrounds, including HEK, CHO, U2OS, 1321N1 and others Cell lines should have confirmed stability past 10 passages. Cell line should be characterized in terms of their pharmacological and biophysical properties using whole-cell patch clamp techniques. Cell lines should be tested and found free of microbial contamination. There should be additional function (pharmacological and electrophysiological) validation on multiple platforms available upon request. There should be direct technical support offered for cell lines for manual patch-clamp and automated patch-clamp technology; cells should be able to be grown and tested in parallel with the customer to troubleshoot any cell culture or expression issues, and to assist customers in ion channel in electrophysiology assay design. A full-time electrophysiologist with at least 25 years of experience should be available to assist with assay design and troubleshooting. 

See below for the attached Statement of Work (SOW) for all details of required products equipment. 

EVALUATION OF PROPOSALS: Vendors shall be evaluated based on the proposals that are the technically acceptable and Lowest Price Technically accectpable (LPTA) to the Government. 

The Associated North America Industry Classification Code (NAICS) is 325414 - Biological Product (except Diagnostic). The Business Size Standard is 1250 employees. Contractor shall provide a unit price for in accordance with SOW.

Requirement:
The provision at FAR 52.212-2 - Evaluation -- Commercial Items, applies to this acquisition. The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The lowest price technically acceptable (LPTA) process described in FAR 15.101-2 will be used, meaning the award will be made on the basis of the lowest evaluated price of proposals meeting or exceeding the acceptability standards. The technical evaluation will be a determination based on information furnished by the Contractor. The Government is not responsible for locating or securing any information which is not identified in the offer. The Government reserves the right to make an award without discussions. In order to be considered technically acceptable, Contractor responses must provide:
a. Information in enough detail to show that the Contractor is able to meet the requirements.Previous acquisitions, history, ability to fulfill requirement in addition to specificiations and equipment in accordance with PWS.
b. Point of contact name and contact information, company CAGE code, UEI number, DUNS number, and TIN.
Partial quotes will not be evaluated by the Government.

SUBMISSION PROCEDURES:
All questions regarding this solicitation must be submitted to the Contract Specialist via email no later than 1:00 p.m. Eastern Time, 7 September 2022, to robert.j.rogers41.civ@army.mil.
Responses to this solicitation must be signed, dated, and received no later than 1:00 p.m. Eastern Time, 14 September 2022. Responses must be sent by email directly to the Contract Specialist, Rob Rogers at robert.j.rogers41.civ@army.mil and Contracting Officer, Rex Valdez, rex.m.valdez2.civ@army.mil. All quotations from responsible sources will be fully considered. Contractors who are not registered in the System for Award Management (SAM) database prior to award will not be considered. Contractors may register with SAM online for free at www.sam.gov.
FAR 52.252-1 - Solicitation Provisions Incorporated by
Reference:
This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at the following address: Acquisition.GOV | www.acquisition.gov
The following clauses and provisions are incorporated by reference:
FAR 52.203-6, Restrictions on Subcontractor Sales to the Government, Alternate I FAR 52.204-7, System for Award Management
FAR 52.204-10, Reporting Executive Compensation and First-Tier Subcontract Awards FAR 52.204-13, System for Award Management Maintenance
FAR 52.209-6, Protecting the Governments Interest When Subcontracting with Contractors Debarred, Suspended, or Proposed for Debarment
FAR 52.212-1, Instructions to Offerors- Commercial Items FAR 52.212-2, Evaluation- Commercial Items
FAR 52.212-3, Offeror Representations and Certifications - Commercial Items FAR 52.212-4, Contract Terms and Conditions - Commercial Items
FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items (Deviation 2013-O0019)
FAR 52.219-6, Notice of Total Small Business Set-Aside FAR 52.219-8, Utilization of Small Business Concerns FAR 52.219-13, Notice of Set-Aside of Orders
FAR 52.219-14, Limitations on Subcontracting
FAR 52.219-28, Post-Award Small Business Program Representation FAR 52.222-3, Convict Labor
FAR 52.222-19, Child Labor- Cooperation with Authorities and Remedies FAR 52.222-21, Prohibition of Segregated Facilities
FAR 52.222-26, Equal Opportunity
FAR 52.222-35, Equal Opportunity for Veterans
FAR 52.222-36, Affirmative Action for Workers with Disabilities FAR 52.222-37, Employment Reports on Veterans
FAR 52.223-18, Encouraging Contractor Policies to Ban Text Messaging While Driving FAR 52.225-13, Restrictions on Certain Foreign Purchases
FAR 52.225-25, Prohibition on Contracting with Entities Engaging in Certain Activities or Transactions Relating to Iran-Representation and Certifications
FAR 52.232-33, Payment by Electronic Funds Transfer- System for Award Management FAR 52.232-39, Unenforceability of Unauthorized Obligations
FAR 52.233-1, Disputes
FAR 52.233-2, Service of Protest FAR 52.233-3, Protest After Award
FAR 52.233-4, Applicable Law for Breach of Contract Claim
FAR 52.239-1, Privacy or Security Safeguards
FAR 52.243-1, Changes- Fixed Prices FAR 52.247-34, FOB- Destination
FAR 52.249-8, Default (Fixed-Price Supply and Service)
DFARS 252.203-7000, Requirements Relating to Compensation of Former DoD Officials
DFARS 252.203-7002, Requirement to Inform Employees of Whistleblower Rights
DFARS 252.204-7003, Control of Government Personnel Work Product
DFARS 252.204-7012, Safeguarding of Unclassified Controlled Technical Information
DFARS 252.204-7015, Disclosure of Information to Litigation Support Contractors
DFARS 252-211-7003, Item Identification and Valuation
DFARS 252.216-7006, Ordering
DFARS 252.225-7012, Preference for Certain Domestic Commodities
DFARS 252.225-7048, Export-Controlled Items
DFARS 252.232-7003, Electronic Submission of Payment Requests and Receiving Reports
DFARS 252.232-7006, Wide Area WorkFlow Payment Instructions
DFARS 252.232-7010, Levies on Contract Payments
DFARS 252.243-7002, Requests for Equitable Adjustment
DFARS 252.243-7001, Pricing of Contract Modifications
DFARS 252.244-7000, Subcontracts for Commercial Items
DFARS 252.247-7023, Transportation of Supplies by Sea
EXEMPTION CERTIFICATE FROM MARYLAND RETAIL SALES AND USE TAX (JUL 1999) (APG 52.0229-4100) Exemption Certificate No. 30005004 covers exemption from Maryland Retail Sales and Use Tax. AMC-LEVEL PROTEST PROGRAM (AUG 2012)
For questions concerning this solicitation, contact Rob Rogers, Contract Specialist, at robert.j.rogers41.civ@army.mil
TELEPHONE REQUESTS WILL NOT BE HONORED.