Brand name or equal, Reagent needed for amplification of DNA for next generation sequencing in high-throughput assay for chromatin for The National Center for Advancing Translational Sciences (NCATS)

Federal Business Opportunities (FBO)

SOURCES SOUGHT NOTICE

1. Solicitation Number: 75N95025Q00122
2. Title:  Brand name or equal, Reagent needed for amplification of DNA for next generation sequencing in high-throughput assay for chromatin for The National Center for Advancing Translational Sciences (NCATS)
3. Classification Code:  6640
4. NAICS Code:  541714 - Research and Development in Biotechnology (Except Nanobiotechnology)  Dollars or Number of Employees: 1,000 employees

Description: 

The purpose of this requisition is to procure Brand name or equal, Reagent needed for amplification of DNA for next generation sequencing in high-throughput assay for chromatin for The National Center for Advancing Translational Sciences (NCATS)

Background: 

The National Institutes of Health (NIH) is the nation’s leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people’s health and save lives.

The National Center for Advancing Translational Sciences (NCATS) is a part of the National Institutes of Health (NIH), whose mission it is to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions.

In doing so the collaborative team aims to develop a high-throughput chromatin assay.  The reagent has been used in the optimization phase of the protocol and this purchase will provide material for high-throughput screening.

Purpose and Objectives:

Brand name or equal, Reagent needed for amplification of DNA for next generation sequencing in high-throughput assay for chromatin for The National Center for Advancing Translational Sciences (NCATS)

Project requirements:

NEBNext Ultra II Q5 Master Mix

500 mL M0544B Bulk order 

Salient characteristics

The characteristics at the minimum shall meet the following requirements:

2X master mix contains dNTPs, Mg++ and a proprietary buffer, and requires only the addition of primers and DNA template for robust amplification, hot start formulation.

Anticipated period of performance:

Anticipated to be delivered approximately 21 days ARO

Place of Delivery:

The place of delivery shall be:

9800 Medical Center Dr Bldg B Rockville, MD 20850

Other important considerations: Independently and not as an agent of the Government, the Contractor shall furnish all the necessary services, qualified personnel, material, equipment, and facilities, not otherwise provided by the Government as needed to perform the work mentioned above.

Capability statement /information sought. Respondents must provide clear and convincing documentation of their capability of providing the services specified in this notice. Also, information must be provided in sufficient details of the respondents’ (a) staff expertise, including their availability, experience, formal and other training; (b) current in-house capability to perform the work; (c) prior completed projects of similar nature; (d) corporate experience and other management capability; and (e) examples of prior completed Government contracts, references, and other related information.

The respondent must also provide their  DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements.

One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2” x 11” paper size, with 1” top, bottom, left and right margins, and with single or double spacing.

The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein.  A cover page and an executive summary may be included but is not required.

The response is limited to ten (10) page limit.  The 10-page limit does not include the cover page, executive summary, or references, if requested.

The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.

All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer.  Facsimile responses are NOT accepted.

The response must be submitted to Giuliana Faller, Contract Specialist at e-mail address Giuliana.faller@nih.gov.

The response must be received on or before January 22, 2025, at 9 am Eastern Time.

 “Disclaimer and Important Notes:  This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work.

Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).”