Brand-name or Equal: Evident Scientific, Inc. ’s Olympus Automated VS200 Slide Scanner System

Closed Solicitation Posted

Solicitation number
75N95024Q00571
Agency
Responses due
Set-aside
No set-aside

Opportunity facts

Place of performance
Bethesda, Maryland, United States

Notice details come from SAM.gov. Updated .

About this opportunity

The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), is seeking to procure an Evident Scientific, Inc.'s Automated VS200 Slide Scanner System or an equal brand-name product. The slide scanner is required by NINDS' Cellular Neurophysiology Section to efficiently image and analyze mouse brain sections as part of their research on dopamine neurons and Parkinson's disease. Key requirements include specific microscope objectives, fluorescence filter sets, a color camera, and software capabilities such as 3D deconvolution and automatic scanning. The acquisition will be evaluated on a lowest price technically acceptable basis, with responses due by 9:00 AM Eastern Time on September 16, 2024. The contract will be a firm fixed-price purchase order for delivery and installation within 120 days.

There is no set-aside designation for this procurement. The incumbent or current contractor is likely Evident Scientific, Inc. as the brand-name item. The government is seeking to acquire one (1) slide scanner system, with a place of performance in Bethesda, MD. The acquisition is being conducted under simplified acquisition procedures for commercial products, with a NAICS code of 334516 (Analytical Laboratory Instrument Manufacturing) and a PSC code of 6640 (Laboratory Equipment and Supplies).

Notice text

2 versions

Update #2 · Latest ·

Amendment 001 to extend the submission due date.

The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH), conducting research into the causes, treatment, and prevention of neurological disorders and stroke. The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease.

The Cellular Neurophysiology Section (CNS) research in 12 focuses on circuit and cellular properties of dopaminergic neurons located in the midbrain. We are interested in the physiology of a subset of dopamine neuron located in the substantia nigra pars compacta (SNc) that undergo selective cell death in Parkinson’s patients.  Specifically, we are interested in understanding how synaptic and intrinsic conductances differ among subpopulations dopamine neurons with the hope that this may provide insight to why SNc dopamine neurons are particularly vulnerable in Parkinson’s disease.  Our goal is to identify novel physiological and genetic markers in single SNc dopamine neurons which may be useful in defining subpopulations of these neurons in a meaningful way. 

The Cellular Neurophysiology Section requires a Evident Scientific, Inc.’s Automated VS200 Slide Scanner System microscopy to analyze mouse brain sections. The automated slide scanner allows CNS lab members to image up to 6 slides at a time with minimal human hours; maybe 15-20 minutes of initial setup, then the entire slide will be imaged overnight. Using a traditional microscope, it would take one of the CNS lab members ~1 full day to image all of the brain sections on 1 slide. With an automated slide scanner, 6 slides can be imaged overnight, and the decrease in time at the microscope allows lab members to be more efficient with their projects. Thus, the automated slide scanner will significantly increase the CN’s productivity.

Update #1 ·

The National Institute of Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH), conducting research into the causes, treatment, and prevention of neurological disorders and stroke. The NINDS mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease.

The Cellular Neurophysiology Section (CNS) research in 12 focuses on circuit and cellular properties of dopaminergic neurons located in the midbrain. We are interested in the physiology of a subset of dopamine neuron located in the substantia nigra pars compacta (SNc) that undergo selective cell death in Parkinson’s patients.  Specifically, we are interested in understanding how synaptic and intrinsic conductances differ among subpopulations dopamine neurons with the hope that this may provide insight to why SNc dopamine neurons are particularly vulnerable in Parkinson’s disease.  Our goal is to identify novel physiological and genetic markers in single SNc dopamine neurons which may be useful in defining subpopulations of these neurons in a meaningful way. 

The Cellular Neurophysiology Section requires a Evident Scientific, Inc.’s Automated VS200 Slide Scanner System microscopy to analyze mouse brain sections. The automated slide scanner allows CNS lab members to image up to 6 slides at a time with minimal human hours; maybe 15-20 minutes of initial setup, then the entire slide will be imaged overnight. Using a traditional microscope, it would take one of the CNS lab members ~1 full day to image all of the brain sections on 1 slide. With an automated slide scanner, 6 slides can be imaged overnight, and the decrease in time at the microscope allows lab members to be more efficient with their projects. Thus, the automated slide scanner will significantly increase the CN’s productivity.

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