Acquisition of Keyence BZ-X1000 All-in-One Fluorescence Microscope for NHGRI Research

Closed Pre-Solicitation Posted

Solicitation number
75N98026Q00712
Agency
Responses due
Set-aside
No set-aside

Opportunity facts

Place of performance
Bethesda, Maryland 20892, United States

Notice details come from SAM.gov. Updated .

About this opportunity

Written by GovTribe AI ·

The National Institutes of Health National Human Genome Research Institute (NHGRI) intends to solicit a Keyence BZ-X1000 All-in-One Fluorescence Microscope or equivalent system by July 7, 2026. No set-aside applies.

The system will be delivered, installed, and configured at NHGRI's designated location to support ongoing and future research activities. NHGRI requires high-resolution fluorescence and brightfield imaging of biological specimens, including fixed cells, live cells, and tissue sections from pre-clinical mouse models. The microscope must provide high-sensitivity fluorescence detection suitable for low-signal biological samples, automated image acquisition and stage control, integrated quantitative image analysis software, multi-channel fluorescence imaging capability, and data export compatibility with standard analysis workflows. The system shall enable visualization and quantification of gene expression, vector distribution, cellular pathology, and therapeutic response while reducing dependency on shared imaging facilities and improving turnaround time for time-sensitive experiments.

The contractor shall deliver all necessary components, accessories, and software licenses for full system functionality; perform system testing and ensure operational readiness; provide user training for NHGRI personnel; and provide warranty and technical support as specified in the contract. The contractor may propose the Keyence BZ-X1000 or an equivalent system meeting all specified requirements.

Notice text

Statement of Need and Objectives  

The purpose of this acquisition is to procure a Keyence BZ-X1000 All-in-One Fluorescence Microscope to support ongoing and future NHGRI research activities. 

Objectives include: 

  • Enable high-resolution fluorescence and brightfield imaging of biological specimens, including fixed cells, live cells, and tissue sections from pre-clinical mouse models. 

  • Support visualization and quantification of gene expression, vector distribution, cellular pathology, and therapeutic response. 

  • Enhance experimental efficiency, reproducibility, and data quality through integrated imaging, automation, and analysis capabilities. 

  • Reduce dependency on shared imaging facilities and improve turnaround time for time-sensitive experiments. 

  • The system shall meet or exceed the following requirements: 

  • All-in-one fluorescence and brightfield microscope system 

  • High-sensitivity fluorescence detection suitable for low-signal biological samples 

  • Capability to image fixed and live cells, as well as tissue sections 

  • Automated image acquisition and stage control 

  • Integrated quantitative image analysis software 

  • High-resolution imaging suitable for cellular and subcellular visualization 

  • User-friendly interface to enable operation by laboratory personnel 

  • Capability for multi-channel fluorescence imaging 

  • Data export and compatibility with standard analysis workflows 

  • Provide the Keyence BZ-X1000 All-in-One Fluorescence Microscope or equal system meeting all specified requirements 

  • Deliver, install, and configure the system at the designated location 

  • Provide all necessary components, accessories, and software licenses required for full system functionality 

  • Perform system testing and ensure operational readiness 

  • Provide user training for NHGRI personnel 

  • Provide warranty and technical support as specified in the contract 

  • General Contractor Responsibilities  

    The Contractor shall: 

  • Provide the Keyence BZ-X1000 All-in-One Fluorescence Microscope or equal system meeting all specified requirements 

  • Deliver, install, and configure the system at the designated location 

  • Provide all necessary components, accessories, and software licenses required for full system functionality 

  • Perform system testing and ensure operational readiness 

  • Provide user training for NHGRI personnel 

  • Provide warranty and technical support as specified in the contract.

Files

File Type Posted
Requirement rev5.docx DOCX document

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