7K20--Illumina brand Genomic Analysis System VA-25-00056640

The Department of Veterans Affairs Technology Acquisition Center is procuring an Illumina brand Genomic Analysis System to support high-throughput genomic analysis capabilities for the Center for Data and Computational Sciences. The procurement seeks 8 Illumina DRAGEN Servers v4, professional informatics services, and DRAGEN Server licenses capable of processing whole genome sequencing, variant calling, and multi-omics analysis with a throughput capacity of 2,000,000 Gb. The system must include dedicated FPGA hardware, integrated genomic workflows, pharmacogenomic star allele callers, and the ability to process one whole genome sequence in approximately 30 minutes while supporting up to 175,000 samples annually. Market research conducted from March to July 2025 determined that only Illumina, Inc. could meet the VA's technical requirements for an out-of-the-box, validated appliance solution. The solicitation deadline was September 4, 2025, with delivery expected within 120 days of contract award.

This procurement does not utilize any set-aside designations and represents a sole source award to Illumina, Inc. following competitive market research that evaluated multiple vendors including QIAGEN, Dell/Falcon Computing, and cloud-based solutions. The total estimated contract value is $19.5 million, with the initial justification document citing $1,983,683.34 including options, covering a 12-month base period and two additional 12-month option periods. The contract includes comprehensive technical specifications for oncology sequencing, transcriptomic RNA analysis, epigenetic analysis, and pharmacogenomic testing capabilities with high accuracy standards for variant calling. The system will be delivered with a one-year manufacturer warranty and next business day replacement parts, with the VA maintaining on-premises data control for their genomic analysis operations.