Sol_75N98026Q00838.pdf

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National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N98026Q00838

JOHN JOHNSON

+10

000-000000

07/20/2026

07/27/2026 1400 ED

Multiple

This is a Sources Sought notice. This is

NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to provide a Basic fluorescence micro-endoscope.

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NSN 7540-01-152-8067

75N98026Q00838

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Document Type: Sources Sought Notice

Solicitation No. 75N98026Q00838

Project Title: Basic fluorescence micro-endoscope

Classification Code: 6640 – LABORATORY EQUIPMENT AND SUPPLIES

NAICS Code: 334516- analytical laboratory instruments and instrumentation systems

Contracting Office Address:

Hospital and Laboratory Support Division Office of Logistics and Operations (OLAO) Office of Acquisition and Logistics Management (OALM) Office of the Director National Institutes of Health Direct: 667-312-5580 251 Bayview Blvd STE 200 BRC Bldg. RM 04A328 Baltimore MD 21224

DESCRIPTION:

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement, to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Small businesses are encouraged to respond.

BACKGROUND:

The Neuronal Circuits and Behavior Unit (NCBU) of the Cellular Neurobiology Research Branch (CNRB), National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH), uses a combination of state-of-the-art optogenetic, electrophysiology, two-photon fluorescence endomicroscopy, immunohistochemistry, and behavioral assays to elucidate the neuronal basis of survival behaviors, such as feeding, and determine how these behaviors are disrupted in eating disorders and drug addiction.

PURPOSE AND OBJECTIVES:

The purpose of this acquisition is to procure a Basic fluorescence microendoscope for our ongoing work investigating neuronal circuits that contribute to opioid use disorder and natural/motivated behaviors such as feeding and fight-or-flight.

Purchase Description:

• Fluorescence Microscope Driver – Gen 3 with integrated LISER and 470nm LED light Source

(FMD3_LISER_LED470)

• LISER Bandpass Filter: 612 nm / 69 nm, 25.0 mm Dia. (LBPF_612/069)

• Fluorescence Microscope Holder (FMH_400)

• Mono Fiberoptic Patchcord (MFP_400/430/LWMJ-0.48_1m_FC-FC)

• Clamp for Fluorescence Microscope Holder (CLAMP_FMH)

• Assisted 1x1 Pigtailed Fiber-optic & Electric Rotary Joints - 24 contacts, HDMI + 4 auxiliary contact connectors, 400 um NA0.57 fibre, 1m input, optimized for fiber photometry & microscopy (AHRJ-OE_1x1_PT_400-0.57_FC_24_HDMI+4)

• Mono Fiberoptic Patchcords (MFP_400/430/LWMJ-0.48_1m_FC-CM3, MFP_400/430/LWMJ- 0.48_1m_FC-FC and MFP_480/500/1000-0.63_1m_FC-CM3)

• Dummy Twist-on Microscope Body, type L (eDTMB-L)

• efocus Optogenetically Synchronized Fluorescence Microscope Body Gen 3 - GCaMP/NpHR (eTOSFM3_445/616)

• Electrical cable for efocus Fluorescence Microscope Body Gen 3 (UFGJ_1000)

• Twist-on Imaging Cannula, Model L-V, 0.5mm, Depth range: 2.7mm – 5.7mm (eTICL_V_500)

• Twist-on Reduced Footprint Imaging Cannula and Twist-on Imaging Cannula, Model L-V, with fluid injector

• Protrusion Adjustment Ring Set (PARS_L)

• USB3.0 Behavior Tracking Camera system Color (BTC_USB3.0_CO)

• Gentec-EO Pronto-SI Power Meter + SM1 Treaded adaptor + 2.5mm receptacle + 1.25mm receptacle

• High performance workstation set up for Doric's systems Processor : AMD Ryzen 9 9950X. 16-core, RAM: 2x32GB DDR5 5600, Graphic Card: GeForce RTX 5060 Ti 16GB GDDR7, Storage: SSD 4TB NVMe + Hard Drive 4TB, Win11 Pro11 Pro Display, keyboard and mouse not included

Salient characteristics:

• System uses eFocus electrowetting lenses that permit Z-space adjustments of up to 300 microns.

• Adjustments can be made while the mouse is awake and performing a behavioral task.

• Equipped with a large (650 x 650 micron) field of view, which is important for maximizing the number of neurons in an analysis.

• eFocus cannula includes a “twist-on” design that ensures that the miniscope can be quickly and securely attached and detached from the mouse with minimal restraint.

• The software used for image acquisition, Doric Neuroscience Studio, is available for free with free upgrades.

Quantity: one set

INSTRUCTIONS:

Capable Vendors shall demonstrate and document in the submitted Capability Statement its experience in the technical areas, requirements, and personnel listed above.

The Government will assess the appropriateness of professional and technical personnel classifications.

The Government will consider any other specific and relevant information about this particular announcement that would improve our evaluation of respondents. Organizations should demonstrate capability to administer and coordinate interrelated tasks in an effective and timely manner.

Documentation may include, but is not limited to, contracts in which the organization performed equivalent tasks (Government and commercial); references, i.e., names, titles, telephone numbers and any other information serving to document the organizations capability; and awards or commendations.

Companies that believe they possess the capabilities to provide the required services should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately. Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Capability statements must also include the Company Name, Unique Entity ID from SAM.gov, Physical Address, and Point of Contact Information. The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.

Interested companies are required to identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number.

The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required.

The response is limited to twenty (20) page limit. The 20-page limit does not include the cover page, executive summary, or references, if requested.

All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted.

The response must be submitted to John Johnson, Contract Specialist at e-mail: johnsonjr@mail.nih.gov

The response must be received on or before July 27th, 2026, 2:00 P.M., Eastern Time.

Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work.

Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published in www.sam.gov. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).”

POINTS OF CONTACT:

Primary Point of Contact:

John Johnson Program Specialist johnsonjr@mail.nih.gov Phone: 667-312-5580 mailto:johnsonjr@mail.nih.gov mailto:johnsonjr@mail.nih.gov

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