All of Us Biobank - FAQs - 2 December 18 2024.pdf

This document contains Questions and Answers (FAQ) for the NIH All of Us Biobank Research Opportunity Announcement (ROA) OTA-25-002, issued on December 18, 2024. The FAQ clarifies key requirements including biospecimen collection details, storage locations, and transition planning.

The FAQs reveal that blood, urine, and saliva samples are currently stored in Rochester, MN and Jacksonville, FL facilities, with approximately 75% in Minnesota and 25% in Florida. Storage volumes include 8.6M 1.0ml blood tubes, 1.0M 0.5ml tubes, 430K 2.5ml tubes, and 440K 5.0ml tubes for blood samples, 200K DNA samples from saliva, and 3.7M urine samples. All freezers are currently awardee-owned. The program utilizes five distinct biospecimen collection kits and processes 800-1,200 participant collections daily. Questions must be submitted by December 13, 2024, and proposals are due December 27, 2024, with no extensions being granted. The FAQs also address automation capabilities, sample labeling requirements, and geographic dispersion preferences for secondary storage facilities, with a preference for locations approximately 2,700 miles apart to mitigate disaster risks.