Notice of Intent-75N98026Q01045.pdf

Notice of Intent to Sole Source

Solicitation Number: 75N98026Q01045 Solicitation Type: Sole Source (Non-Competitive) Title: Odyssey® M multimodal imaging system NAICS / Size Standard: 334516/ 1,000 employees

Introduction

THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO

AWARD A PURCHASE ORDER WITHOUT PROVIDING FOR FULL AND OPEN

COMPETITION. The National Heart, Lung, and Blood Institute (NHLBI), Office of Acquisitions (OA), intends to negotiate and award a purchase order on a noncompetitive sole source basis to LI-COR

BIOTECH, LLC to provide Odyssey® M multimodal imaging system to the Division of Intramural

Research in accordance with the following information.

Background Information

The NHLBI currently utilizes an aging LI-COR Odyssey platform and requires an updated system. The

Odyssey® M is a multimodal imaging system designed for high-sensitivity fluorescence and optional chemiluminescence imaging. It supports near-infrared and visible fluorescence, RGB true-color imaging, and optional luminescence detection, with calibrated integrated imaging channels for consistent performance across assays. The system uses an sCMOS image sensor, line-scanning technology, and 5-micron resolution to support high-sensitivity, high-dynamic-range imaging in minutes rather than hours.

Purpose and Objectives

The purpose of this acquisition is to acquire an Odyssey® M multimodal imaging system designed for high-sensitivity fluorescence and optional chemiluminescence imaging.

Contractor Requirements

The Contractor shall provide one (1) Odyssey M - Chemi/Flour – Academic and shall include:

Imaging Modalities

The system supports NIR fluorescence, visible fluorescence, RGB imaging, and optional chemiluminescence/luminescence imaging. The fluorescence plus chemiluminescence model includes 19 total channels, while the fluorescence-only model includes 18 total channels.

Detector System

The Odyssey M uses an sCMOS image sensor for fluorescence imaging and a CCD sensor for chemiluminescence detection.

Resolution

The system provides selectable resolution settings of 5, 10, 20, 50, or 100 µm, allowing users to optimize image detail and acquisition speed depending on the assay.

Dynamic Range

The Odyssey M provides greater than 6 logs of dynamic range for fluorescence and optional chemiluminescence imaging, obtained in a single acquisition.

Sole Source Justification

The NHLBI research laboratory requires the procurement of the LI-COR Odyssey M Imaging System to directly replace the existing, highly utilized LI-COR Odyssey platform, which is over 10 years old and has reached the end of its operational lifecycle. Ongoing longitudinal studies rely on historical datasets spanning over a decade, procuring an alternative system from a different vendor would introduce unacceptable risks, including platform-dependent variability in detector sensitivity, dynamic range, and imaging algorithms that would create systemic batch effects and compromise data comparison.

Furthermore, staying with LI-COR preserves compatibility with established workflows, trained personnel, proprietary reagents, and dedicated analysis software, thereby preventing costly assay re-validation and project delays. Ultimately, the LI-COR Odyssey M is uniquely required to ensure data continuity, technical consistency, and the validity of longitudinal research comparisons across experiments.

Regulatory Authority

This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart

12.102 (a), restricting competition. For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available.

FAR Clauses

The provision at FAR clause 52.212-1, Instructions to Offerors – Commercial Products and Commercial

Services, applies to this acquisition.

The provision at FAR clause 52.212-2, Evaluation – Commercial Products and Commercial Services, is applicable. The Government will award a contract resulting from this notice to the offeror listed above.

The following factors shall be used to evaluate the offer: The contractor shall demonstrate its ability to provide the services listed that meets the specifications provided above.

FAR clause 52.212-3, Offeror Representations and Certifications – Commercial Items, is applicable. An offeror shall complete only paragraphs (b) of this provision if the offeror has completed the annual representations and certificates electronically via http://www.acquisition.gov. If an offeror has not completed the annual representations and certifications electronically at the System for Award

Management (SAM) website, the offeror shall complete only paragraphs (c) through (p) of this provision.

FAR clause at 52.212-4, Contract Terms and Conditions – Commercial Items, applies to this acquisition.

FAR clause at 52.204-13 System for Award Management Maintenance, applies to this acquisition.

The provisions at FAR clause 52.203-17, Contractor Employee Whistleblower Rights, applies to this acquisition.

The provisions at FAR clause 52.222-41, Service Contract Labor Standards, applies to this acquisition.

The provision at FAR clause 52.225-25, Prohibition on Contracting With Entities Engaging in Certain Activities or Transactions Relating to Iran—Representation and Certifications, applies to this acquisition.

FAR clause FAR 52.232-33, Payment by Electronic Funds Transfer—System for Award Management, applies to this acquisition.

HHSAR clause 352.239-78, Information and Communication Technology Accessibility Notice

HHSAR clause 352.239-79, Information and Communication Technology Accessibility

HHSAR clause 352.232-71, Electronic Submission of Payment Requests

Additional Information

The North American Industry Classification System (NAICS) Code is 334516 and the Small Business Size

Standard is 1,000 employees. This acquisition is being conducted under RFO FAR Part 12, Acquisition of

Commercial Products and Commercial Services, therefore the requirements of FAR Part 6, Competitive

Requirements, are not applicable and the resultant award will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2026-01 effective March 13, 2026.

This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Unique Entity Identifier

(UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All responses must be received by September 08, 2026, at 12:00PM ED and must reference synopsis number 75N98026Q01045. Responses shall be submitted electronically to noelle.decenzo@nih.gov.

Responses will only be accepted if dated and signed by an authorized company representative. All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.

http://www.sam.gov/ mailto:noelle.decenzo@nih.gov