Pre-Sol_Notice_for_N02CO87001-94.pdf

“SOURCE SELECTION INFORMATION – SEE FAR 2.101 AND 3.104.”

Pre-Solicitation Notice: RFP No. N02CO87001-94

Title: NCI Genomic Characterization Centers

Contracting Office Address

Department of Health and Human Services, National Institutes of Health (NIH), National Cancer Institute (NCI), Office of Acquisitions, Riverside Five, 8490 Progress Drive, Suite 400, Frederick, MD 21701-4998.

Note: This synopsis follows Small Business Sources Sought (SBSS) notice that was released on January 16, 2018 under HHS-NIH-NCI-SBSS-TSB-87001-94.

Description

The Center for Cancer Genomics (CCG) provides genomic characterization services through several Genomic Characterization Centers (GCC) to NCI programs and deposits the resulting data in the Genomic Data Commons, a large-scale database of cancer genomic data for public use.

This is a non-Research and Development, Indefinite Delivery/Indefinite Quantity (IDIQ) requirement, which will provide for firm fixed unit price type task orders to be placed. This solicitation will include three separate IDIQ pools (DNA characterization pool, RNA characterization pool, and Protein characterization pool).

The objective of this project is to acquire high-resolution, systematic, comprehensive (genome-wide) characterization services of cancer-related genomic alterations. The contractor(s) shall function as a fundamental resource and play a key role in the CCG research programs. Key goals shall include ensuring that standards are developed, implemented, continually improved, and maintained to support the entire genomic characterization pipeline. Study variables shall be minimized with rigorous Quality Assurance/Quality Control of all parts of the operation.

The contractor(s) shall offer the types of characterizations using validated methods in a high-throughput fashion at the start of the project. The biomaterial for these studies (DNA, RNA, or Protein) will be provided by the Biospecimen Processing Centers (BPC) of CCG. The aim is to have all molecular characterizations conducted on biomolecules from the same biospecimens for optimal analytical integration for data comparability.

The contractor(s) shall support all genomics projects with following services in scope:

1. Receive biomaterial from BPC

2. Operate molecular characterization pipelines

3. Improve and optimize performance of characterization pipelines

4. Implement quality control procedures

5. Support informatics and data delivery

6. Perform transition activities

“SOURCE SELECTION INFORMATION – SEE FAR 2.101 AND 3.104.”

Multiple awards are anticipated for each pool, although not every offeror who submits a technically acceptable proposal will necessarily be chosen for award. It is estimated that approximately ten IDIQ base contracts will be awarded, among the three IDIQ pools.

This is an existing requirement currently supported through subcontracts that were awarded under the Federally Funded Research and Development Center (FFRDC) contract number HHSN261200800001E, the Frederick National Laboratory for Cancer Research, operated by Leidos Biomedical Research, with a period of performance of 09/26/2008 – 08/30/2019. The contract is entitled “Operations and Technical Support Services at NCI-Frederick” at the

FFRDC.

Leidos subcontract numbers and periods of performance are listed below:

• The Broad Institute of MIT and Harvard = 15X054, 6/24/2015 – 8/30/2019

• MD Anderson Cancer Center = 15X140, 6/19/2015 – 8/30/2019

• University of North Carolina = 16X250, 11/17/2016 – 8/30/2019

• Stanford University = 17X029, 1/1/2017 – 8/30/2019

• Baylor University = 17X184, 10/25/2017 - 8/30/2019

The solicitation is anticipated to result in up to ten IDIQ contracts being awarded across the three pools (DNA, RNA and Protein). Each base IDIQ contract will be for five years with awards anticipated on or before July 31, 2019 to offerors capable of performing the work.

This advertisement does not commit the United States Federal Government to award any contract. The 2017 NAICS code for this acquisition is 541990 with a size standard of $15.0 million. THIS ACQUISTION IS UNRESTRICTED (NOT A SET-ASIDE FOR SMALL

BUSINESSES).

The Request for Proposal (RFP) N02CO87001-94 is scheduled for electronic release on or about 11/20/2018 and receipt of proposals will be due at 3:00 pm ET on or about 2/18/2019.

The RFP will only be available electronically and must be accessed through the Office of Acquisitions, NCI homepage by using the following address: http://rcb.cancer.gov/rcb-internet/ or through FedBizOpps.gov https://www.fbo.gov/. All information required for submission of a proposal will be contained in the electronic RFP package. No collect calls will be accepted. No facsimile transmissions will be accepted. It is the offeror’s responsibility to monitor the above-mentioned sites for release of the solicitation and any amendments. All responsible sources may submit a proposal, which shall be considered by the agency. POTENTIAL OFFERORS

WILL BE RESPONSIBLE FOR DOWNLOADING THEIR OWN COPY OF THE SOLICITIATION

AND ANY AMENDMENTS THAT MAY BE ISSUED. FAILURE TO DO SO WILL BE AT THE

FIRM’S OWN RISK. ALL INQUIRIES SHALL BE SUBMITTED ELECTRONICALLY TO THE

CONTRACTING OFFICER LISTED AS THE POINT OF CONTACT HEREIN.

Point of Contact: Alexis Hudak, Contract Specialist at email alexis.hudak@nih.gov http://rcb.cancer.gov/rcb-internet/ https://www.fbo.gov/ mailto:alexis.hudak@nih.gov