Compiled Answers.xlsx
XLSX spreadsheet 88 KB Posted
- Attached to
- PTAG RFI - Cheminformatics Solution
- Solicitation number
- ACQ250051
About this file
The file is a compiled set of Questions and Answers (Q&A) related to a Request for Information (RFI) for a cheminformatics software solution for the United States Patent and Trademark Office (USPTO). The USPTO seeks a unified software platform for 251 patent examiners and Patent Business employees, with specific technical requirements including chemical search tool integration, batch conversion of chemical names to structures, chemical property calculations, and Markush group enumeration functionality.
Key technical specifications include property predictors such as pKa, logP, logD, molecular weight, and boiling/melting points, with the ability to connect to external search tools like SciFinder and PubChem. The licensing will be for concurrent use, with no expected user base expansion during option years. The response deadline for the Self-Attestation Common Form is June 9, 2025, at 10:00 ET, with PDF submissions to be emailed to david.hill@uspto.gov and brian.carper@uspto.gov. The solicitation number is ACQ250051 and is classified as a pre-solicitation opportunity under the Department of Commerce US Patent and Trademark Office.
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Other files
| File | Type | Posted |
|---|---|---|
| RFI Attachment 1 - RFI Response Template V2.xlsx | XLSX spreadsheet | |
| RFI Attachment 3 - Self-Attestation Common Form.docx | DOCX document | |
| RFI Attachment 4 - Question and Answer Sheet.xlsx | XLSX spreadsheet | |
| PTAG RFI Cheminformatics Software.docx | DOCX document | |
| RFI Attachment 2 - Cheminformatics SOW Draft 2May2025.docx | DOCX document |
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Sheet1
| Question # | Reference | Question Category (Contract or Technical) | Question | Answer |
| 1 | 3.1.2.5. Add on to connect/integrate with other chemical search tools (e.g SciFinder, PubChem….)., | Technical | Please provide further details regarding the nature of outside search tools. |
Are USPTO-hosted copies of the databases with SQL access available?
| Do they require direct (REST) API access to the third party data source? | There are no USPTO hosted copies of the data base. Access to third party data source is required. | ||||
| 2 | 3.1.2.3 Batch conversion of a large list of chemical names to chemical structures. Patent claims often list hundreds of chemical compound names with no structures. This feature makes it possible to easily convert each name to chemical structure. | Technical | What is the typical volume of chemical compound names you are looking to run in a single batch when converting names to chemical structures? | ||
| What are the performance considerations, upper limit? | Typically between 10 and 50 in a single batch, normally does not exceed 100. Performance considerations: 1-2 minutes upper limit to precisely draw chemical structures. | ||||
| 3 | 3.1.2.8 Chemical and physical property calculations | Technical | Which property predictors specifically are required? | Property Predictors: pKa, logP, logD, logS, molecular weight, boiling point, melting point, heat of formation. Although not exclusive, these are the ones we commonly use. | |
| 4 | 3.1.1.1 Provide cheminformatics software solution for two hundred and fifty-one (251) patent examiners and Patent Business employees to efficiently keep track of their work, visualize and gain a deeper understanding of their results and correlate biological activity with chemical structures. | Contract | Is the USPTO seeking a single, unified platform to meet all requirements, or is it open to modular solutions where specific functionality can be integrated into existing systems? | A single unified platform. | |
| 5 | 3.1.2.7 | Technical | What are the specific expectations for Markush group enumeration functionality? | The ability to take a Markush depiction of a structural formula with defined R groups and convert this to discrete structural depictions of each possible combination. | |
| 6 | 3.1.1.1 Provide cheminformatics software solution for two hundred and fifty-one (251) patent examiners and Patent Business employees to efficiently keep track of their work, visualize and gain a deeper understanding of their results and correlate biological activity with chemical structures. | Contract | Are licenses expected to be concurrent or named user licenses? | Concurrent use | |
| 7 | 3.1.1.1 Provide cheminformatics software solution for two hundred and fifty-one (251) patent examiners and Patent Business employees to efficiently keep track of their work, visualize and gain a deeper understanding of their results and correlate biological activity with chemical structures. | Contract | Will the user base expand during the option year periods, or should pricing account for scalablity? | At this time the USPTO does not expect the user base to expand | |
| 8 | RFI Attachment 3 - Self-Attestation Common Form | Contract | What is the deadline to submit the Attestation Common Form? | Responses are due June 9, 2025 @ 10:00 ET to be included in the vendor responses | |
| 9 | RFI Attachment 3 - Self-Attestation Common Form | Contract | Who should we email the PDF form to, if not using the online portal? | Please send a copy of the PDF to david.hill@uspto.gov and brian.carper@uspto.gov |
File details come from the government source that posted it. Updated .