A23 Attachment 2a Assay Testing Requirements.xlsx

XLSX spreadsheet 22 KB Posted

Attached to
ADAPT Contract Research Organization Support Services
Solicitation number
75N992-25-SN-103
Issued by

About this file

This file is an Excel spreadsheet template titled "Assay Testing Requirements" that appears to be Attachment 2a to solicitation 75N992-25-SN-103. The template is designed to collect information about various types of assay testing capabilities, specifically focused on whole exome sequencing. It includes columns for respondents to indicate their testing specifications across multiple parameters including: assay name and manufacturer details, testing entity information, CLIA certification status, coverage metrics (with preferred levels of >100x, >150x, and >200x), gene quantity capabilities (preferred levels of >15k, >16.5k, and >20k), and average turnaround time in days. The template also includes sections for indicating whether specifications meet "Preferred" or "Strongly Preferred" thresholds for coverage levels ranging from 500x to 2000x and gene quantities from 500 to over 15,000.

This template is part of a draft solicitation from the Department of Health and Human Services National Institutes of Health seeking feedback on ADAPT Contract Research Organization Support Services. While the template itself doesn't specify required services, it indicates the government's interest in gathering information about advanced genomic testing capabilities from potential contractors.

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Other files

File Type Posted
A23 Attachment 2 Assay Testing Worksheet.xlsx XLSX spreadsheet
A23 Attachment 3 HHS Subcontracting Plan Template.docx DOCX document
A23 Attachment 1 Price Template.xlsx XLSX spreadsheet
A23 75N99225R00002 DRAFT.pdf PDF

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Text version

Sheet1

Type of assayAssay Name and details (manufacturer, version)Name of entity that is performing the testCLIA-certified lab (yes/no; provide license number)Coverage (e.g., 1000x)Number of genes (maximum capability)Average Turnaround Time (days)
MeetsPreferredStrongly PreferredMeetsPreferredStrongly PreferredMeetsPreferredStrongly Preferred
whole exome sequencingY/N>100x>150x>200x>15k>16.5k>20k<14 days<12 days<8 days
whole transcriptome sequencingY/N50M reads>75M reads>100M reads>15k>16.5k>20k<14 days<12 days<8 days
ctDNA-seqY/N>500x>1000x>2000x>500>1,000>15,000<14 days<12 days<8 days
ctDNA methylomeN/A (RUO allowed)>500x>1000x>2000x>500>1,000>15,000<14 days<12 days<8 days
cfMeDIP-seq***N/A (RUO allowed)>500x>1000x>2000x>500>1,000>15,000<35 days<28 days<14 days
M= million
k= thousand
N/A= not applicable
*RUO = Research Use Only
**Average Turnaround Time is based on Offeror receipt of sample
***Optional; Not required for table completion

File details come from the government source that posted it. Updated .