Statement of Work SOW - LifeCanvas Technologies Laboratory Testing Services.docx
DOCX document 51 KB Posted
- Solicitation number
- 75N98026Q00887LIFECANVASTECHNOLOGIESINC
About this file
This is a Statement of Work (SOW) for whole brain mouse light sheet brain imaging services to be provided to the National Institute on Alcohol Abuse and Alcoholism (NIAAA) at the National Institutes of Health. The service will analyze whole brain activity changes from genetically modified mouse lines maintained by the Section on Neural Circuits, with rapid turnaround being critical due to age-sensitive experiments requiring results within one month of sample receipt. The contractor will receive mouse brain samples shipped in tubes and perform comprehensive processing including tissue clearing, light-sheet imaging, and segmentation of the brain into over 820 anatomical regions. Deliverables include CVF files containing both raw cell counts and counts normalized per area, with data transferred to NIH-supplied hard drives for shipment to the research team.
The period of performance spans July 2026 through July 2027, and the contract is structured as a firm fixed-price purchase order. Key contractor responsibilities include receiving and logging incoming samples, performing tissue clearing and sample preparation, conducting whole-brain light-sheet imaging, segmenting brains into defined anatomical regions, generating standardized output files with raw and normalized cell counts, and maintaining archived data and physical samples for a minimum of one year to permit retesting. No training is required under this SOW. The Department of Health and Human Services' National Institutes of Health Office of Logistics and Acquisition Operations is the federal agency managing this procurement.
View the file
On GovTribe
Work with this file
- Download the original file
- Contacts named in this file
- Similar government files
- Ask GovTribe AI about this file
Text version
STATEMENT OF WORK (SOW)
1.0 TITLE
Whole brain mouse light sheet brain imaging service
2.0 BACKGROUND
The imaging service will be used to analyze changes in whole brain activity from genetically modified mouse lines maintained by the Section on Neural Circuits at the NIAAA, NIH. Accurate imaging of brain activity is essential it forms the foundation for all downstream experimental analyses. Without this information, we cannot proceed with our experiments, as the validity of our data depends on the ability to quantify phenotypic differences based on genotype.
Rapid turnaround is also critical, as some experiments are age-sensitive and require genotyping results within 1 month of sample receipt. The brain tissue samples to be processed by clearing and light sheet imaging will be collected by the Lead Project Manager (LPM), and trainees in the Section on Neural Circuits at the NIAAA.
3.0 TYPE OF ORDER
This is a:
· Firm Fixed-Price Purchase Order, T&M, Labor Hour, etc.
· Severable or Non-Severable
4.0 SCOPE OF WORK/TASKS
Whole brains are shipped to the company in tubes. The company processes the samples by clearing the tissue and performing light-sheet imaging. The brain is segmented into over 820 regions, and CVF files containing both raw counts and counts per area are provided. Results must be delivered within one month of sample arrival. Data are shipped to us on an NIH-supplied hard drive, and both the results and brain samples are retained by the company for at least one year to allow for any necessary retesting.
The following tasks are required to fulfill this requirement:
· Receive and log incoming brain samples.
· Perform tissue clearing and prepare samples for imaging.
· Conduct whole-brain light-sheet imaging.
· Segment the brain into defined anatomical regions (>820 areas).
· Generate CVF files with raw and normalized cell counts.
· Transfer data to an NIH-provided hard drive and ship to the research team.
· Maintain archived data and physical samples for a minimum of one year.
4.1 DELIVERABLES
The samples for processing will be collected by the Lead Project manager/LPM and trainees in the section on Neural Circuits of the NIAAA. The company will ship the data containing results to the address of the section on Neural Circuits.
4.3 TRAINING
None.
5.0 PERIOD OF PERFORMANCE
July 2026- July 2027
File details come from the government source that posted it. Updated .