Sol_75N98026Q00462.pdf

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National Institutes of Health OD - Office of Logistics and Acquisition Operations 6100 Executive Blvd., Room 6B05 Bethesda, MD 20892-7511

75N98026Q00462

BRITTANY MAY

+10

000-000000

05/29/2026

06/12/2026 1730 ED

Multiple

The purpose of this Competitive Combined

Synopsis/Solicitation is to procure One

(1) Tunable Multi-Photon Microscope.

1 6

07/18

COMPETITIVE COMBINED SYNOPSIS/SOLICITATION

INTRODUCTION

This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested, and a separate written solicitation will not be issued.

The solicitation number is 75N98026Q00462. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.

This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 334516 with a Size Standard of 1000.

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2026-01 effective March 13, 2026.

• This requirement is unrestricted.

DESCRIPTION OF REQUIREMENT

The National Institute of Mental Health (NIMH), Systems Neurodevelopment Laboratory (SNL), requires one (1) Tunable Laser Multi-Photon Microscope for shared use and collaborations on multiple protocols and projects. Current microscopes are no longer sufficient to support and supplement the labs current two-photon microscope system. Allowing monitoring and manipulation large neonural populations at a single-cell resolution, giving the lab greater versatility in experiments, greater penetration of tissue, use of multiple fluorescent indicators, and stimulation of different wavelength-sensitive options.

SALIENT CHARACTERISTICS

The Tunable Laser Microscope must meet the following minimum characteristics:

• Wide Tuning Range o Gap-free light source 680 nm to 1300 nm tuning range (nearly double the accessible wavelengths compared to traditional lasers). Optimized performance is in the 900–1100 nm range to support the common green and red fluorescent proteins including GFP, RFP, GCaMP, jRGECO, and mCherry. It is important that increased output power, experiments using red flurophores in the 1200–1300 nm range can be performed.

• Dual Output o Both lasers can be equipped with a fixed 1045 nm dual beam option to support the diverse needs of multimodal imaging. The tunable and fixed outputs are synchronized which enables several applications including advanced imaging techniques such as CARS and SRS.Supports simultaneous, multi-wavelength excitation of fluorophores and/or genetically encoded calcium indicators, and second and third harmonic generation microscopies.

▪ main output: 680-1300 nm tunable range, dual output: 1045 nm

(fixed) wavelength

▪ Average Power: main output, >1.4W (700nm), >2.1W (800nm), >2.6W (900nm), >2.2W (1000nm), >2.0W (1100nm), >1.7W (1200nm), >1.2W (1300nm); dual output, >3.0W (1045nm)

▪ Pulse width: main output, <120fs; dual output, <170 fs

▪ Precompensation dispersion range: 680nm (0 fs2 to -25,000 fs2), 800nm (0 fs2 to -17,000 fs2), 900nm (0 fs2 to -12,000 fs2), 1050nm (0 fs2 to -5,500 fs2), 1300nm (0 fs2 to -4,500 fs2)

▪ 80 MHz repetition rate

▪ 1.1 +/- 0.3 mm bean diameters

• Integrated dispersion compensation ensures pulse broadening effects are minimized. As a result, fluorescence signal and penetration depth are maximized.

The integrated attenuators provide real-time adjustment of the output energy delivered to the sample. Their fast response time acts as a software-controlled switch that can be used to minimize exposure for delicate samples and to minimize backlash effects.

• Integrated attenuator o Attenuated or real-time optimization of the experimental pulse energy.

Delivers high average power, short pulses and dispersion compensation to support the most demanding experiments in neuroscience, immunology and biology. Their fast response time acts as a software-controlled switch that can be used to minimize exposure for delicate samples and to minimize backlash effects. Achieves shortest pulses to the sample to enable deep tissue imaging with lower risk of optical damage.

▪ <500ns rise time

▪ 1000:1 contrast ratio

▪ 0.1% min control step

▪ 0-10V analog control

▪ 10 kOhm input impedance

• Hands-free, fully computer-controlled light source. Must be equipped with real-time optimization for consistent output performance and day-to-day reliability.

• One-Year Comprehensive warranty after installation

The provision at FAR 52.212-1, Instructions to Offerors—Commercial Items, applies to this acquisition. Add any agency-specific instructions as required.

The provision at FAR 52.212-2, Evaluation—Commercial Items, applies to this acquisition.

The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation represents the best value to the Government, price and other factors considered.

Evaluation Factors:

• Price

• Technical capability

• Past performance

• Delivery schedule (Include relative importance of factors if required.)

A written notice of award or acceptance of an offer, issued within the time specified in the offer, shall result in a binding contract without further action by either party. The Government reserves the right to accept any offer before the expiration date.

Offerors shall include a completed copy of FAR 52.212-3, Offeror Representations and Certifications—Commercial Items, with their offer.

FAR 52.212-4, Contract Terms and Conditions—Commercial Items, applies to this acquisition.

FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders—Commercial Items, applies to this acquisition.

Additional contract requirements or terms and conditions, as determined necessary by the Contracting Officer and consistent with customary commercial practices:

(Insert if applicable; otherwise state “None.”)

The Defense Priorities and Allocations System (DPAS) is (applicable / not applicable).

SUBMISSION REQUIREMENTS

Responses to this synopsis must include sufficient information to demonstrate the offeror’s bona-fide capabilities for fulfilling the required product or service. Responses must include, at a minimum:

• Unit and total price

• Shipping and handling costs

• Delivery period after award

• Delivery terms

• F.O.B. point (destination or origin)

• Product or catalog numbers (if applicable)

• Product/service description

Additional evaluation considerations may include past performance, warranty, lifecycle cost, maintenance availability, and environmental or energy efficiency.

Responses must include the Unique Entity Identifier (UEI), Taxpayer Identification Number (TIN), and business size certification. All offerors must be actively registered in the System for Award Management (SAM) at www.sam.gov.

All responses must be received by June 12, 2026 at 5:30 PM EST and must reference solicitation number 75N98026Q00462. Responses must be submitted via the SAM.gov webportal. Potential Offerors do not need to register to view a notice; however, in order to submit questions and/or response to this Notice, an account will need to be established.

(The NIH is not responsible for any electronic transmission, or mail failures, resulting in failed or late quotes).

POINT OF CONTACT

Brittany May Contract Specialist Brittany.may@nih.gov http://www.sam.gov/ mailto:Brittany.may@nih.gov

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