Preclinical efficacy & intermediate endpoint biomarkers IDIQ contract in support of the prevent cancer preclinical drug development program

Active Awarded Last action

Contract number
75N91024D00005
Awardee
Awarding agency
Task orders
3 $3,142,485 obligated

Award facts

Opportunity
Combined order value
  • $3,142,485 Current, with exercised options
  • $4,268,745 Potential, with all options
Last date to order 55% complete
IDV ceiling 2% used
$149,995,000.00
Award type
Multiple award
Who can order
Only the awarding agency
Set-aside
No set-aside
Competition
Full and Open Competition · 9 offers Negotiated Proposal / Quote
Pricing
Order Dependent (IDV only)
Legislative mandates

Award details come from SAM.gov/FPDS.

About this IDV

The National Cancer Institute awarded an indefinite delivery contract to University Of Oklahoma Health Sciences Center on January 25, 2024, with a ceiling of $149,995,000 and an ultimate completion date of January 24, 2029. This is a multiple-award vehicle with no set-aside.

Place of performance is Oklahoma City, Oklahoma. The IDIQ procures preclinical drug development research, including evaluation of efficacy and pharmacodynamic biomarkers for potential cancer preventive agents in support of the PREVENT Cancer Preclinical Drug Development Program.

The originating pre-solicitation was posted December 19, 2022, with a due date of February 6, 2023. Delivery orders issued under this IDIQ include a $1,886,811.80 firm fixed price order awarded June 17, 2024, for development of a novel multivalent mRNA vaccine targeting triple-negative breast cancer, with ultimate completion June 16, 2026, and a $1,234,179 firm fixed price order awarded September 25, 2025, for further development of mitochondria-targeted honokiol for prevention of lung cancer adenocarcinoma and squamous cell carcinoma, with ultimate completion March 24, 2028. Both orders are performed in Oklahoma City.

Task orders

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00005 · EO 14398; preclinical efficacy & intermediate endpoint biomarkers IDIQ contract in support of the prevent cancer preclinical drug development program $0
Supplemental Agreement for work within scope P00004 $0
Supplemental Agreement for work within scope P00003 $0
Other Administrative Action P00002 $0
Supplemental Agreement for work within scope P00001 $0
Original award $0

Subawards

Subcontractor Amount Awarded
The Methodist Hospital Research Institute Base IDIQ title: prevent cancer preclinical drug development program: preclinical efficacy and intermediate endpoint biomarkers $1,122,335
The Methodist Hospital TO TITLE: A NOVEL MRNA VACCINE TO PREVENT TRIPLE NEGATIVE BREAST CANCER IDIQ TITLE: PREVENT CANCER PRECLINICAL DRUG DEVELOPMENT PROGRAM: PRECLINICAL EFFICACY… $693,916

Quick answers

Who was awarded contract 75N91024D00005?

75N91024D00005 was awarded to University Of Oklahoma by National Cancer Institute (National Institutes of Health) on January 25, 2024.

How much is contract 75N91024D00005 worth?

Orders under 75N91024D00005 have obligated $3,142,485. Their combined potential value, with all options, is $4,268,745. 75N91024D00005's own ceiling is $149,995,000.

How many orders have been placed under contract 75N91024D00005?

3 orders have been placed under 75N91024D00005, the latest on September 14, 2026.

Who can order from contract 75N91024D00005?

75N91024D00005 is a multiple award indefinite delivery contract. Only the awarding agency can place orders on it.

Is contract 75N91024D00005 part of a contract vehicle?

Yes. 75N91024D00005 is part of PRECLINICAL EFFICACY & INTERMEDIATE ENDPOINT BIOMARKERS IDIQ.

Was contract 75N91024D00005 competed?

The extent of competition for 75N91024D00005 was full and open competition. The government received 9 offers.

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