T cells in the brain (TCB2027): decoding T cell targets in neurodegeneration

Active Project Grant Awarded Last action

Award ID
R13AG104346
Recipient
Awarding agency
Obligated
$50,000

Award facts

Assistance listing
93.866 Aging Research
Completion date 17% complete
Place of performance
Scottsdale, AZ 85259, USA

Award details come from USAspending.gov.

Description

Abstract
T cells are key contributors to neuroinflammation and neurodegeneration, yet identifying their targets and antigen specificities in human neurological disease remains a major challenge. Rapid advances in neuroimmunology, including single-cell multiomics, TCR repertoire sequencing, and antigen-discovery platforms, have begun to reshape our understanding of T cell biology in the CNS. Building on the success of TCB2024 and TCB2025, which each convened over 200 national and international attendees, the T cells in the brain series has established itself as the premier forum for integrating T cell biology with human neurodegeneration. These meetings generated new multi-institutional collaborations, fostered technology exchange among immunologists, neuropathologists, T cell engineers, and computational biologists, and supported several emerging joint grant applications and shared datasets. "T cells in the brain (TCB2027): decoding T cell targets in neurodegeneration" will advance this momentum by consolidating recent progress and promoting interdisciplinary discussion toward precision T-cell-based therapies. TCB remains committed to active efforts to engage trainees, and junior researchers. By uniting interdisciplinary expertise and strengthening collaborative networks, TCB2027 aims to accelerate the development of effective T cell-based interventions for neurodegenerative disorders.

Quick answers

Who received award R13AG104346?

R13AG104346 was awarded to Mayo Clinic Arizona by National Institute on Aging (National Institutes of Health) on September 5, 2026.

How much is award R13AG104346 worth?

$50,000 has been obligated on R13AG104346.

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