Optimizing a BIO-behavioral intervention to promote viral suppression among HIV+ people who inject drugs on the U.S.-mexico border - 7. Project summary/abstract the primary goal of the proposed…

Optimizing a BIO-behavioral intervention to promote viral suppression among HIV+ people who inject drugs on the U.S.-mexico border - 7. Project summary/abstract the primary goal of the proposed research is to build an optimized intervention to promote sustained viral suppression among a group of latinx people who inject drugs and who are living with HIV on the U.S.-mexico border. We are using the multiphase optimization strategy (MOST). MOST is an engineering-inspired framework for designing and building optimized interventions. The primary aim is to conduct a 2-to-4 factorial design where participants are randomized to zero or up to four intervention conditions (each condition comprises a different set of intervention components). The four components are receiving (or not receiving) peer support services for medication-assisted treatment (mat) uptake and persistence, behavioral activation therapy for depression (BAT), life-steps medication adherence program, and patient navigation for HIV care. The intervention is being implemented at programa compañeros, a community-based social service organization in cuidad, juarez, chihuahua, mexico, a city nestled alongside EL paso, texas. Participants will complete a baseline survey assessment, complete their assigned intervention programs, and then return for 6- ,9-, and 12-month follow-up assessments. The primary outcome is sustained viral suppression defined as viral load test results of…