Project Grant R01AT014237
- The National Heart, Lung, and Blood Institute awarded Mayo Clinic $242,100 on August 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate treatment-resistant insomnia, with work completed by July 31, 2028. Mayo Clinic will define and quantify the prevalence of treatment-resistant insomnia in a real-world clinical sample using electronic health record data from the Mayo Clinic Biobank and Mayo Clinic Tapestry Project, supplemented by chart review validation....
- The National Institute of Mental Health awarded Mayo Clinic $301,092 on May 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop real-time behavioral intervention technology for children with severe emotional and behavioral disturbance. The project develops generative algorithms using smartwatch data and parent-provided feedback to predict and individualize interventions when a child displays disruptive behavior or temper outbursts. The first aim builds algorithms...
- The National Institute of Environmental Health Sciences, part of the National Institutes of Health within the Department of Health and Human Services, awarded Mayo Clinic $764,848 on September 9, 2025, under the Medical Library Assistance program (CFDA 93.879) to conduct a multicenter randomized clinical trial of virtual world-based cardiac rehabilitation designed to promote data-powered cardiovascular health among cardiac patients. The project runs through July 31, 2029, with performance at...
- The National Institute of Neurological Disorders and Stroke awarded Mayo Clinic $622,784 on July 21, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate acute and chronic repercussions of spinal cord stimulation following spinal cord injury. The research quantifies blood pressure instability after spinal cord injury, which interrupts descending autonomic regulatory signals and causes loss of consciousness, stroke,...
- The National Center for Complementary and Integrative Health awarded $831,984 to Scripps Research Institute on April 17, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to investigate the neural mechanisms by which the interoceptive system co-regulates emotional and autonomic responses. The research addresses the coupling between emotion and autonomic control—phenomena such as anxiety elevating blood pressure, stress inducing sighing, and...
- The National Heart, Lung, and Blood Institute awarded Mayo Clinic $593,663 on August 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate thrombolysis resistance in acute ischemic stroke with large vessel occlusion. The project addresses the failure of intravenous thrombolysis with tissue plasminogen activator (TPA) to achieve successful recanalization in most eligible patients. Mayo Clinic will conduct three integrated research activities: define metabolic...
- The National Institute on Aging at the Department of Health and Human Services awarded Mayo Clinic $878,516 in project grant funding on June 15, 2026, under the Aging Research program (CFDA 93.866) to conduct a six-week clinical study examining high-resistance inspiratory muscle strength training as an intervention to reduce sympathetic nerve activity and improve sleep in postmenopausal women experiencing hot flashes. The research addresses vasomotor symptoms associated with menopause, which...
- The National Institute of Biomedical Imaging and Bioengineering awarded Mayo Clinic $625,527 on April 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to develop methods for non-invasive coronary artery imaging using photon-counting detector CT and artificial intelligence. The award funds research to overcome limitations in cardiac CT imaging that prevent accurate visualization of coronary stenosis in patients with...
- The National Institute of Biomedical Imaging and Bioengineering awarded Mayo Clinic $620,179 on July 1, 2026, under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to implement, optimize, and validate charge-sharing-correction techniques on a whole-body photon-counting-detector CT scanner for vascular plaque characterization. The project addresses spectral degradation caused by charge sharing in photon-counting-detector CT systems,...
- Mayo Clinic was awarded a $784,182 project grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation. The grant is part of the Computer and Information Science and Engineering program (CFDA 47.070), which supports investigator-initiated research and education in computing, communications, and information science and engineering. Under the grant, Mayo Clinic will conduct collaborative research to develop a causal artificial intelligence digital twin...
The National Center for Complementary and Integrative Health awarded Mayo Clinic $361,732 on August 28, 2026, under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) to investigate how breathing influences brain activity, perception, and decision-making through brain-body integration research. The project collects a multimodal dataset combining physiological monitoring with advanced human brain recordings. Patients undergoing clinical intracranial EEG monitoring and healthy participants measured with scalp EEG and functional near-infrared spectroscopy perform identical visual perception tasks while simultaneous measurements capture respiration, cardiovascular activity, blood oxygenation, and pupil diameter. The work quantifies how breathing couples to neural signals, cerebral hemodynamics, and perceptual task performance by extracting fine-grained physiological features that align with neurovascular processes. Extended visual encoding models incorporate interpretable parameters capturing physiology-driven variability in brain responses, testing how respiration influences trial-to-trial fluctuations in visual responses. Performance occurs in Rochester, Minnesota. The period of performance runs from August 28, 2026, through July 31, 2031. The assistance type is a Project Grant. Mayo Clinic, a tax-exempt nonprofit academic medical center, is the recipient organization.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $361.7k | 9/1/26 |