Mayo Clinic

Mayo Clinic, doing business as College of Medicine, is a non-profit academic medical center and educational institution that provides medical education services, biomedical research, diagnostic laboratory testing, and clinical services to federal agencies primarily as a prime recipient or contractor (93% of recent awards) with no set-aside designations. The organization operates from its Rochester, Minnesota headquarters under a tax-exempt corporate structure and competes in full-and-open federal procurements across education, research, and healthcare service delivery.

Mayo Clinic's federal footprint splits decisively between two customer bases by dollar value. The National Institutes of Health National Cancer Institute dominates by potential value, accounting for six awards worth $10.4 million in combined potential value and anchoring the organization's research capability. The Department of the Navy Bureau of Medicine and Surgery leads by award count with seventeen awards worth $513 thousand combined potential value, concentrated in medical education delivery through a single-award Basic Ordering Agreement (N0018913GZ007) running through September 2034 with recurring delivery orders for tuition and fees. Recent Navy awards include delivery orders placed between December 2022 and July 2024, each valued at $14,722 to $32,342 in tuition support. The Department of Veterans Affairs Veterans Health Administration also places work with the organization, including a $2.8 million clinical services award. Across all named customers, 50% of awards cluster within the top five agencies, while potential value is heavily concentrated in NCI research grants.

Mayo Clinic's capability portfolio reflects its dual role as a research institution and clinical education provider. Education and training work dominates by award count (18 awards under the PSC Education/Training—Tuition/Registration/Membership Fees), with Navy medical officer training as the primary recurring vehicle. Reference laboratory testing comprises eight awards, supporting federal diagnostic and analytical needs. Research and development work includes preclinical evaluations of cancer therapeutics for NCI, diagnostic testing and exosome product development for the Defense Health Agency, and long-term COVID-19 neuroimaging studies performed as a sub-recipient under Regents of the University of Minnesota. Award activity has remained sparse in recent years (one award each in 2019 and 2022, four in 2023, three in 2024, two in 2025), with combined dollars obligated at $3.6 million against $13.8 million in combined potential value. Mayo Clinic holds no major government-wide IDVs or GWACs and operates in subcontract roles on grant research projects led by Dana-Farber Cancer Institute and Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, where site-level research execution and patient recruitment are the primary functions.