Mayo Clinic

Mayo Clinic, doing business as College of Medicine, a non-profit tax-exempt educational institution and academic medical center headquartered in Rochester, Minnesota, operates as a federal prime contractor and grant recipient delivering medical education, biomedical research, and clinical diagnostic services to military and civilian health agencies. The vendor competes in the open market without SBA set-aside designations across 54 awards (93% as prime, 7% as sub-recipient) spanning contract, IDV, and grant vehicles since 2006.

Mayo Clinic's federal footprint divides sharply between two customer streams. The Department of Navy Bureau of Medicine and Surgery anchors the contract base with 17 delivery orders (combined potential value $513 thousand) under a single-award Basic Ordering Agreement (N0018913GZ007) running through September 2034 for tuition and fees supporting Navy medical education programs at the Rochester campus. The National Cancer Institute, however, drives dollar concentration with 6 awards carrying $10.4 million in combined potential value, reflecting Mayo's role as a research partner and sub-recipient on cancer therapeutics evaluation and preclinical research initiatives. The Department of Veterans Affairs Veterans Health Administration VISN 23 holds one award valued at $2.8 million. Across the portfolio, the top customers by potential value account for 99% of dollars; the Navy's volume (50% of awards by count) masks its modest per-award magnitude, whereas NCI's smaller count anchors most of the dollar value. Mayo Clinic also serves 13 distinct federal agencies including the National Institute of Environmental Health Sciences and the Army Installation Management Command, though with minimal dollar exposure outside the Navy and NCI relationships.

Award activity has been sparse and intermittent — one award in 2019, one in 2022, four in 2023, three in 2024, and two in 2025 — with $3.6 million obligated against a $13.8 million combined potential value (26% burn rate). The vendor's capability classification reflects its academic-medical-center structure: Administration of Education Programs (16 awards), Colleges/Universities (6 awards), and Research and Development in Physical/Engineering/Life Sciences (4 awards) dominate NAICS distribution, while Education/Training Tuition/Registration Fees PSC leads at 18 awards, followed by Reference Laboratory Testing (8 awards) and Health R&D Services (3 awards). Recent work includes routine Navy tuition-and-fees delivery orders (sub-$33 thousand each) and multi-year grant sub-awards as site principal investigator for cancer therapeutics research led by Dana-Farber Cancer Institute and biomedical innovation studies under Lundquist Institute for Biomedical Innovation, with Mayo researchers executing tissue acquisition, cell isolation, and clinical translation work at the Rochester campus. Mayo also participates in an estimated multi-year NIH-funded COVID-19 neuroimaging study as a sub-recipient under the University of Minnesota prime award.