Clinical and translational science collaborative of northern ohio, catalyzing linkages to equity in health (CLE health)

Active Cooperative Agreement Awarded Last action

Award ID
UM1TR004528
Recipient
Awarding agency
Obligated
$64,190,683

Award facts

Completion date 47% complete
Place of performance
Cleveland, OH 44106, USA

Award details come from USAspending.gov.

Description

Abstract
For the past 15 years, the clinical and translational science collaborative (ctsc) at case western reserve university (cwru) has linked clinical and translational research efforts at five independent institutions- cwru, cleveland clinic, metrohealth system, university hospitals of cleveland, and louis stokes cleveland veterans affairs medical center. Two new partners (university of toledo school of medicine and northeast ohio medical university) are now being added to extend the ctsc's reach across northern ohio. The cwru ctsc has a strong track record of enhancing the quantity and quality of clinical and translational science (CTS) among our partners by facilitating novel research paradigms, technologies, and training. Our ctsc has developed a new generation of researchers, enhanced collaborations among investigators, streamlined discovery by building partnerships among industry and community and organizational partners, and facilitated many successful entrepreneurial startups. Building on this solid foundation, the cwru ctsc proposes an expanded focus on health equity, reflected in the project theme catalyzing linkages to equity in health (CLE health). Social, economic, and environmental disadvantages are linked to poor health outcomes and lead to disparities in life expectancy, infant mortality, and rates of chronic conditions. Minority groups are often underrepresented in clinical trials as well, meaning there can be insufficient data for understanding the effectiveness or safety of new drugs, procedures, or health interventions for different populations. The overall goals of this project are to 1) understand the fundamental barriers to optimal recruitment of underrepresented groups in clinical trials and test and scale interventions aimed at breaking down these barriers to diversify study engagement, 2) facilitate and expedite innovation in multicenter clinical and translational research by fully integrating community and stakeholder partners and ensuring that this research represents the experiences of all and results in health improvements for all, 3) disseminate and implement novel and responsive research programs across clinical and community settings to advance access to health interventions that aim to promote health equity, and 4) create and disseminate inclusive and high impact educational and training programs for translational research professionals of all disciplines and levels, both in clinical and community settings. The ctsc has designed a strategic management core and six CTS research and training elements to accomplish these goals: workforce development, community & stakeholder engagement, resources & services, CTS pilot, health informatics, and CTS research program. We are committed to innovative and collaborative practice and dissemination of results so that everyone in northern ohio-and beyond-can benefit from advances in CTS in our programs and discoveries.

Transactions

Action Obligated Date
Amendment $0
Amendment $8,031,063
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Amendment $80,480
Amendment $80,480
Amendment $7,822,492
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Amendment $8,041,152
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Amendment $8,078,131
Amendment $8,078,131
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Original award $8,078,131
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Subawards

Subrecipient Amount Awarded
University Of Toledo Subaward between CWRU and University of Toledo. $58,262
Northeast Ohio Medical University Subaward between CWRU and Northern Ohio Medical University. $79,960
University Of Toledo Subaward between CWRU and University of Toledo. $90,542
United Cerebral Palsy Association Of Greater Cleveland Inc. Subaward between CWRU and United Cerebral Palsy Assc of Greater Cleveland. $50,670
Northeast Ohio Medical University Subaward between CWRU and Northeast Ohio Medical University. $69,209
University Of Toledo Clinical and Translational Science Collaboration of Northern Ohio, Catalyzing Linkages $75,846
Hola Ohio $30,000
University Of Toledo Subaward between the University of Toledo and CWRU. $75,846
Northeast Ohio Medical University Subaward between Northeast Ohio Medical University and CWRU. $65,561
Hola Ohio Subaward between HOLA Ohio and CWRU. $30,000
University Of Toledo Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health) - PROJECT SUMMARY/ABSTRACT For the… $76,141
Hola Ohio $30,000
Northeast Ohio Medical University Clinical and Translational Science Collaboration of Northern Ohio, Catalyzing Linkages $65,561
Northeast Ohio Medical University Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health) - PROJECT SUMMARY/ABSTRACT For the… $59,882
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Quick answers

Who received award UM1TR004528?

UM1TR004528 was awarded to Case Western Reserve University by National Center for Advancing Translational Sciences (National Institutes of Health) on August 2, 2023.

How much is award UM1TR004528 worth?

$64,190,683 has been obligated on UM1TR004528.

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